![\"\"](\"http://image.97suifang.com/media/imgs/2013/07/21/23-%E8%A1%A81_2.jpg\")
\r\n\t\r\n\u672c\u7814\u7a76\u6240\u89c2\u6d4b\u7684\u662f\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\uff08\u5355\u836f\u6cbb\u7597\u3001\u5e72\u6270\u7d20\u4e0e\u62c9\u7c73\u592b\u5b9a\u8054\u5408\u6cbb\u7597\u3001\u62c9\u7c73\u592b\u5b9a\u5355\u836f\u6cbb\u7597\u8fd93\u4e2d\u4e0d\u540c\u7684\u65b9\u6cd5\u6cbb\u7597e\u6297\u539f\uff08HBeAg\uff09\u9634\u6027\u6162\u6027\u4e59\u809d\u7684\u6548\u679c\u3001\u5b89\u5168\u6027\u3002
", "publish_date": "2005-03-27", "abstract_result": "24\u5468\u968f\u8bbf\u671f\u7ed3\u675f\u4ee5\u540e\uff0c\u8c37\u4e19\u8f6c\u6c28\u9176\uff08ALT\uff09\u7684\u590d\u5e38\u7387\uff08\u6062\u590d\u6b63\u5e38\u503c\u4ee5\u5185\u7684\u51e0\u7387\uff09\u6216\u8005\u4e59\u809d\u75c5\u6bd2\uff08HBV\uff09 DNA\u6c34\u5e73\u964d\u4f4e\u523020,000\u62f7\u8d1d/mL\u7684\u51e0\u7387\u5728\u63a5\u53d7\u542b\u6709\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\uff08 \u4e0b\u6587\u6b64\u7c7b\u5e72\u6270\u7d20\u90fd\u7b80\u79f0\u4e3a\u201c\u5e72\u6270\u7d20\u201d\uff0c\u5982\u6709\u8bf4\u5230\u666e\u901a\u5e72\u6270\u7d20\u4f1a\u7279\u522b\u6307\u51fa\uff09\u7684\u6cbb\u7597\u7ec4\u4eba\u7fa4\u4e2d\u4f1a\u66f4\u9ad8\uff08\u6bd4\u8d77\u90a3\u4e9b\u4ec5\u7528\u62c9\u7c73\u592b\u5b9a\u7684\u60a3\u8005\uff09\u3002\r\n\r\n\u5728\u7ed3\u675f\u6cbb\u759724\u5468\u540e\uff0c\u75c5\u6bd2\u6c34\u5e73\u964d\u5230400\u62f7\u8d1d/mL\u662f\u5f88\u591a\u4eba\u8ffd\u6c42\u7684\u6cbb\u7597\u7ec8\u70b9\uff0c\u5728\u542b\u6709\u5e72\u6270\u7d20\u7684\u6cbb\u7597\u7ec4\u4eba\u7fa4\u4e2d\u5927\u6982\u670920%\u5de6\u53f3\u83b7\u5f97\u4e86\u8fd9\u6837\u7684\u75c5\u6bd2\u5b66\u5e94\u7b54\uff0c\u4ec5\u7528\u62c9\u7c73\u592b\u5b9a\u7684\u60a3\u8005\u8fd9\u4e2a\u6570\u5b57\u53ea\u67097%\u3002\r\n\r\n\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u7684\u6e05\u9664\uff0c\u53ea\u670912\u4e2a\u4eba\u53d1\u751f\uff08\u90fd\u5728\u542b\u6709\u5e72\u6270\u7d20\u7684\u6cbb\u7597\u7ec4\u4eba\u7fa4\u4e2d\uff0c\u5360\u6bd43.4%\uff09\uff0c\u4ec5\u7528\u62c9\u7c73\u592b\u5b9a\u7684\u6cbb\u7597\u7ec4\u4e2d\u6ca1\u6709\u4eba\u83b7\u5f97HBsAg\u6e05\u9664\u3002", "endpoints": [ 1, 2, 3, 4, 5, 6 ] } }, { "pk": 2, "model": "sciblog.sciblog", "fields": { "subhead": "HBeAg\u9634\u6027\u6162\u4e59\u809d\u60a3\u8005\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u6cbb\u7597\u65f6\uff0c\u65e9\u671f\u53ef\u4ee5\u901a\u8fc7HBsAg\u548cHBV DNA\u7684\u5b9a\u91cf\u6c34\u5e73\u6765\u9884\u6d4b\u4ee5\u540e\u7684\u5e94\u7b54\u6548\u679c", "sample": [], "readed_count": 0, "references": [ 2 ], "catched_by": [], "query": [], "endpoint_content": "\u672c\u7814\u7a76\u6839\u636e\u6b27\u6d32\u809d\u75c5\u534f\u4f1a\u6700\u65b0\u6307\u5357\u4e2d\u5bf9\u4e8e\u6cbb\u7597\u7ec8\u70b9\u4ee5\u53ca\uff08\u805a\u4e59\u4e8c\u9187\uff09\u5e72\u6270\u7d20\u6cbb\u7597\u7684\u75c5\u6bd2\u5b66\u5e94\u7b54\u7684\u5b9a\u4e49\u6765\u786e\u5b9a\u7814\u7a76\u7ec8\u70b9SR\u3002\u672c\u6587\u4e2d\uff0cHBeAg\u9634\u6027\u6162\u6027\u4e59\u809d\u60a3\u8005\u83b7\u5f97SR(sustained response\uff0c\u6301\u7eed\u5e94\u7b54\uff09\u662f\u6307\uff1a\r\n\u968f\u8bbf\u7ec8\u70b9\uff08\u7b2c72\u5468\uff09\u7684\u65f6\u5019\uff0cHBV DNA\u6c34\u5e73\u5c0f\u4e8e10000\u62f7\u8d1d/ml\uff08\u76f8\u5f53\u4e8e1714 IU/mL \uff09\r\n\u968f\u8bbf\u7ec8\u70b9\uff08\u7b2c72\u5468\uff09\u7684\u65f6\u5019\uff0cALT\u6062\u590d\u6b63\u5e38", "treatment_content": "\u60a3\u8005\u6309\u71671\uff1a1\u6bd4\u4f8b\u88ab\u968f\u673a\u5206\u914d\u5230\u4e24\u7ec4\u4eba\u5f53\u4e2d\uff0c\u4e00\u7ec4\u63a5\u53d7180ug/\u6bcf\u5468\u7684\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u8054\u5408\u5229\u5df4\u97e6\u67971000mg/\u6bcf\u5929\uff08\u4f53\u91cd\u5c0f\u4e8e75\u5343\u514b\uff09\u6216\u80051200mg/\u6bcf\u5929\uff08\u4f53\u91cd>=75\u5343\u514b\u7684\uff09\u6cbb\u7597\uff0c\u8fd8\u6709\u4e00\u7ec4\u662f\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20180ug/\u6bcf\u5468\u7684\u5358\u836f\u6cbb\u7597\u3002\r\n\r\n48\u5468\u7597\u7a0b\uff0c\u6cbb\u7597\u7ed3\u675f\u540e\u7ee7\u7eed\u968f\u8bbf\u89c2\u5bdf24\u5468\u3002\r\n\r\n\u75c5\u60a3\u6bcf\u4e2a\u6708\u53c2\u52a0\u4e00\u6b21\u95e8\u8bca\u3002\r\n\r\n\u8868\u9762\u6297\u539f\u5b9a\u91cf\u68c0\u6d4b\u65f6\u95f4\u70b9\uff1a\u6cbb\u7597\u671f\u95f4\u7b2c4\u30018\u300112\u300124\u300136\u300148\u5468\uff0c\u968f\u8bbf\u671f\u95f4\u7b2c60\u300172\u5468\u3002", "baseline": [], "title": "HBeAg\u9634\u6027\u6162\u4e59\u809d\u60a3\u8005\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u6cbb\u7597\u65f6\uff0c\u65e9\u671f\u53ef\u4ee5\u901a\u8fc7HBsAg\u548cHBV DNA\u7684\u5b9a\u91cf\u6c34\u5e73\u6765\u9884\u6d4b\u4ee5\u540e\u7684\u5e94\u7b54\u6548\u679c", "clinic_conditions": [ 13, 14, 15, 16, 17, 18, 19, 20, 21 ], "hospital": [], "source": null, "understanded_count": 0, "safety": "", "entitle": "Early on-treatment prediction of response to peginterferon alfa-2a for hbeag-negative chronic hepatitis b using hbsag and hbv dna levels", "konwledge_piece": [ 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16 ], "method": "\u672c\u7814\u7a76\u60a3\u8005\u90fd\u662f\u63a5\u53d7PEG\u5e72\u6270\u7d20\u6cbb\u7597\u3002", "conclusion": "\u9488\u5bf9\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6cbb\u7597\u7684HBeAg\u9634\u6027\u6162\u4e59\u809d\u60a3\u8005\uff0c\u672c\u7814\u7a76\u5b66\u8005\u5efa\u8bae\u4e86\u4e00\u4e2a\u5728\u6cbb\u7597\u5f00\u59cb\u540e\u7b2c12\u5468\u65f6\u5224\u65ad\u662f\u5426\u9700\u8981\u505c\u836f\u7684\u51c6\u5219\uff0c\u8fd9\u4e2a\u51c6\u5219\u57fa\u4e8e\u8840\u6e05\u4e2dHBV DNA\u548cHBsAg\u4e24\u4e2a\u6307\u6807\u4ece\u57fa\u7ebf\u5f00\u59cb\u7684\u4e0b\u964d\u6c34\u5e73\u3002\u6362\u8a00\u4e4b\uff0c\u4e34\u5e8a\u4e2d\uff0c\u540c\u65f6\u5b9a\u91cf\u68c0\u6d4bHBsAg\u548cHBV DNA\u80fd\u591f\u8c03\u6574\u805a\u4e59\u4e8c\u9187\u6cbb\u7597HBeAg\u9634\u6027\u6162\u4e59\u809d\u7684\u7b56\u7565\u3002\r\n\r\n\u5bf9\u4e8e\u4ee5\u4e0b\u60a3\u8005\uff1a\u6cbb\u7597\u7b2c12\u5468\u65f6\uff0c\u76f8\u6bd4\u57fa\u7ebf\uff08\u6cbb\u7597\u5f00\u59cb\uff09\uff0c\u8840\u6e05HBsAg\u6c34\u5e73\u6ca1\u6709\u4e0b\u964d\u800c\u4e14HBV DNA \u4e0b\u964d<2 log \u62f7\u8d1d/mL \uff0c\u5e94\u8be5\u505c\u6b62\u5e72\u6270\u7d20\u7684\u6cbb\u7597\uff0c\u6362\u7528\u5176\u4ed6\u6cbb\u7597\u65b9\u6cd5\u3002", "detectionAssay": "\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u5b9a\u91cf\u68c0\u6d4b\uff1a\u96c5\u57f9 Architect HBsAg assay (Abbott Laboratories\uff09\u63d0\u4f9b\uff0c \u7ebf\u6027\u8303\u56f4\u662f0.05-250 IU/mL\r\n\u4e59\u809d\u75c5\u6bd2\uff08HBV DNA\uff09\u68c0\u6d4b\uff1a\u7f57\u6c0f\u8bca\u65ad TaqMan HBV assay, Roche Diagnostics\u63d0\u4f9b\uff0c\u68c0\u6d4b\u4e0b\u965035copies/mL\r\n\u8c37\u4e19\u8f6c\u6c28\u9176\uff08ALT\uff09\u68c0\u6d4b\uff1a\u5728\u7814\u7a76\u5f53\u5730\u533b\u9662\u6309\u7167\u6807\u51c6\u64cd\u4f5c\r\n\u4e59\u809d\u75c5\u6bd2\uff08HBV\uff09\u57fa\u56e0\u578b\u68c0\u6d4b\uff1a INNO-LiPA assay (Innogenetics)\r\n\u809d\u7a7f\u523a\u68c0\u6d4b\uff1a\u6bcf\u4e2a\u60a3\u8005\u90fd\u6709\u5165\u7ec4\u524d\u4e00\u5e74\u5185\u7684\u809d\u7a7f\u7ed3\u679c\uff0c\u7528Ishak\u8bc4\u5206\u7cfb\u7edf\u6765\u8868\u793a\u809d\u810f\u708e\u75c7\u7684\u7b49\u7ea7\uff080-18\u5206\uff09\u548c\u809d\u810f\u7ea4\u7ef4\u5316\u7684\u7a0b\u5ea6\uff080-6\u5206\uff09", "ifvalue": 11.0, "journal": "Hepatology", "authors": "Harry Janssen , Vincent Rijckborst\uff0cBettina E. Hansen, Yilmaz Cakaloglu, Peter Ferenci, Fehmi Tabak, Meral Akdogan, Krzysztof Simon, Ulus S. Akarca, Robert Flisiak, Elke Verhey, Anneke J. Van Vuuren, Charles A. B. Boucher, Martijn J. ter Borg Harry L. A. Janssen ", "abstractAE": "", "confused_count": 0, "collected_by": [], "guidline": null, "aim": "\u8fd9\u9879\u7814\u7a76\u662f\u7814\u7a76\u8005\u4e3b\u5bfc\u578b\u3001\u591a\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u5bf9\u7167\u7814\u7a76\uff0c\u8be5\u7814\u7a76\u9075\u5b88\u8d6b\u5c14\u8f9b\u57fa\u5ba3\u8a00\u3002\r\n1.\u7814\u7a76\u7684\u76ee\u7684\u662f\u4e3a\u5f04\u6e05\u695a\u5728\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alpha-2a\u6cbb\u7597\u7684e\u6297\u539f\u9634\u6027\u6162\u4e59\u809d\u60a3\u8005\u4e2d\uff0c\u6cbb\u7597\u524d\u671f\u5b9a\u91cf\u7684\u8840\u6e05HBsAg\u542b\u91cf\u5728\u9884\u6d4b\u4eca\u540e\u6301\u7eed\u5e94\u7b54\u6548\u5e94\u65f6\u7684\u4f5c\u7528\u3002\r\n2. \u9488\u5bf9\u8fd9\u90e8\u5206\u60a3\u8005\u6765\u627e\u5230\u53ef\u9760\u7684\u6cbb\u7597\u6307\u5357\u65b9\u9488\u6765\u6307\u5bfc\u505c\u836f\u3002", "publish_date": "2010-04-19", "abstract_result": "\u56de\u987e\u8be5\u7814\u7a76\u4e2d\u7684\u6301\u7eed\u5e94\u7b54\u8005\u5728\u6cbb\u7597\u671f\u95f4\u7684\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u6c34\u5e73\u7684\u53d8\u5316\uff0c\u4ece\u6cbb\u75978\u5468\u5f00\u59cb\uff0c\u8fd9\u4e9b\u5e94\u7b54\u8005\u7684HBsAg\u7684\u6c34\u5e73\u660e\u663e\u4e0b\u964d\uff1b\u76f8\u53cd\uff0c\u7ed3\u675f\u6cbb\u7597\u540e\u6ca1\u6709\u53d1\u751f\u6301\u7eed\u5e94\u7b54\u7684\u60a3\u8005\u6cbb\u7597\u671f\u95f4HBsAg\u6c34\u5e73\u53ea\u6709\u8f7b\u5fae\u7684\u4e0b\u964d\u3002\r\n\r\n\u6839\u636e\u7edf\u8ba1\u5b66\u5904\u7406\uff0c\u6216\u8005\u8bf4\u901a\u8fc7\u53d7\u8bd5\u8005\u5de5\u4f5c\u66f2\u7ebf\u7684AUC\u5224\u65ad\uff0c\u4ec5\u4ec5\u4f9d\u9760HBsAg\u7684\u4e0b\u964d\u9884\u6d4b\u6301\u7eed\u5e94\u7b54\u6709\u9650\u5236\u3002\r\n\r\n\u628aHBsAg\u4e0b\u964d\u548c\u4e59\u809d\u75c5\u6bd2\uff08HBV 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"ifvalue": 2.6, "journal": "Hepatol Int. 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"sample": [], "indicators": [], "type": null } }, { "pk": 5, "model": "sciblog.resultcontent", "fields": { "card_content": "", "blog": 2, "shorttitle": "", "abstract": "", "content": "$\u6cbb\u7597\u7b2c12\u5468\uff0c\u76f8\u5bf9\u5f00\u59cb\r\nHBsAg\u6ca1\u6709\u4e0b\u964d\u4e14DNA\u4e0b\u964d\u8f83\u5c0f\r\nHBsAg\u6ca1\u6709\u4e0b\u964d\u4f46DNA\u4e0b\u964d\u8f83\u5927\r\nHBsAg\u53d1\u751f\u4e0b\u964d\u4f46DNA\u4e0b\u964d\u8f83\u5c0f\r\nHBsAg\u53d1\u751f\u4e0b\u964d\u4e14DNA\u4e0b\u964d\u8f83\u5927$\r\n$$\u54ea\u79cd\u60a3\u8005\u6301\u7eed\u5e94\u7b54\u51e0\u7387\u6700\u5927\uff0c\u54ea\u79cd\u6700\u5c0f\uff1f$$\r\n$$$\u8868\u9762\u6297\u539f HBsAg \r\n\u4e59\u809d\u75c5\u6bd2HBV DNA\r\n\u8c37\u4e19\u8f6c\u6c28\u9176 ALT$$$\r\n\r\n\u4ee5\u4e0b\u54ea\u90e8\u5206\u60a3\u8005\u968f\u8bbf\u7ed3\u675f\u65f6\u83b7\u5f97\u6301\u7eed\u5e94\u7b54\u7684\u51e0\u7387\u6700\u9ad8\uff1f\u8c01\u53c8\u6700\u4f4e\uff1f\r\n\u6839\u636e\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u548c\u4e59\u809d\u75c5\u6bd2\uff08HBV DNA\uff09\u4e0b\u964d\u7a0b\u5ea6\u5206\u7ec4\uff1a\r\n\u6cbb\u7597\u5f00\u59cb\u540e\u7b2c12\u5468\u65f6\uff0c\u76f8\u6bd4\u57fa\u7ebf\u6c34\u5e73\uff08\u6cbb\u7597\u5f00\u59cb\uff09\uff0c\r\nHBsAg\u6ca1\u6709\u4e0b\u964d\u4e14DNA\u4e0b\u964d\u7a0b\u5ea6\u5c0f\u4e8e2\u4e2alog \u62f7\u8d1d/mL\uff1b\r\nHBsAg\u6ca1\u6709\u4e0b\u964d\u4f46DNA\u4e0b\u964d\u7a0b\u5ea6\u5927\u4e8e\u6216\u8005\u7b49\u4e8e2\u4e2alog \u62f7\u8d1d/mL\uff1b\r\nHBsAg\u53d1\u751f\u4e0b\u964d\u4f46DNA\u4e0b\u964d\u7a0b\u5ea6\u5c0f\u4e8e2\u4e2alog \u62f7\u8d1d/mL\uff1b\r\nHBsAg\u53d1\u751f\u4e0b\u964d\u4e14DNA\u4e0b\u964d\u7a0b\u5ea6\u5927\u4e8e\u6216\u8005\u7b49\u4e8e2\u4e2alog\u62f7\u8d1d/mL\r\n\u8fd9\u56db\u7c7b\u60a3\u8005\u3002", 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HBsAg$$$\r\n\r\n\u6cbb\u7597\u7ed3\u675f6\u4e2a\u6708\u540ee\u6297\u539f\u8840\u6e05\u5b66\u8f6c\u6362\u548c\u6ca1\u6709\u53d1\u751f\u8f6c\u6362\u7684\u60a3\u8005\uff0c\u4ed6\u4eec\u57fa\u7ebf\u53ca\u6cbb\u7597\u671f\u95f4\u51e0\u9879\u6307\u6807\u6c34\u5e73\u7684\u5dee\u5f02\r\n\u672c\u6587\u628a\u6cbb\u7597\u7ed3\u675f6\u4e2a\u6708\u540ee\u6297\u539f\uff08HBeAg\uff09\u53d1\u751f\u8840\u6e05\u5b66\u8f6c\u6362\u5b9a\u4e49\u6210\u83b7\u5f97\u5e94\u7b54\u3002\r\n\r\ne\u6297\u539f\u8840\u6e05\u5b66\u8f6c\u6362\u4e0e\u672a\u8f6c\u6362 \uff0c\u57fa\u7ebf\u65f6\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u6709\u5dee\u5f02\r\n\r\n\u6cbb\u7597\u7ed3\u675f\u540e\u83b7\u5f97\u6cbb\u7597\u5e94\u7b54\u7684\u60a3\u8005\u7684\u57fa\u7ebf\uff08\u5373\u6cbb\u7597\u5f00\u59cb\uff09\u8868\u9762\u6297\u539f\u6c34\u5e73\uff0c\u6bd4\u8d77\u90a3\u4e9b\u6ca1\u6709\u83b7\u5f97\u5e94\u7b54\u7684\u60a3\u8005\u7684\u57fa\u7ebf\u8868\u9762\u6297\u539f\u6c34\u5e73\u8981\u4f4e\u3002\uff083.97 log10 IU/mL \u6bd4 4.21 log10IU/mL\uff09\u3002\r\n\r\ne\u6297\u539f\u8840\u6e05\u5b66\u8f6c\u6362\u4e0e\u672a\u8f6c\u6362\uff0c\u6cbb\u7597\u671f\u95f4\u8868\u9762\u6297\u539f\u4e0b\u964d\u7a0b\u5ea6\u7684\u4e0d\u540c\r\n\r\n\u5728\u6cbb\u7597\u7ed3\u675f\u540e6\u4e2a\u6708\u53d1\u751fe\u6297\u539f\uff08HBeAg\uff09\u8840\u6e05\u5b66\u8f6c\u6362\u7684\u60a3\u8005\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u7684\u4e0b\u964d\u7a0b\u5ea6\u5728\u6cbb\u7597\u5f00\u59cb\u540e12\u5468\u300124\u5468\u300124\u5468\u300148\u5468\u548c\u6cbb\u7597\u7ed3\u675f6\u4e2a\u6708\uff08\u4e5f\u5c31\u662f72\u5468\uff09\u8981\u6bd4\u6ca1\u6709\u53d1\u751f\u8fc7\u8840\u6e05\u5b66\u8f6c\u6362\u7684\u4eba\u5927\u3002\r\n\r\ne\u6297\u539f\u8840\u6e05\u5b66\u8f6c\u6362\u4e0e\u672a\u8f6c\u6362\uff0cHBV 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"fields": { "card_content": "", "blog": 3, "shorttitle": "", "abstract": "", "content": "<br data-mce-bogus=\"1\">", "sample": [], "indicators": [], "type": null } }, { "pk": 9, "model": "sciblog.resultcontent", "fields": { "card_content": "", "blog": 3, "shorttitle": "", "abstract": "", "content": "<br data-mce-bogus=\"1\">", "sample": [], "indicators": [], "type": null } }, { "pk": 10, "model": "sciblog.resultcontent", "fields": { "card_content": "", "blog": 3, "shorttitle": "", "abstract": "", "content": "<br data-mce-bogus=\"1\">", "sample": [], "indicators": [], "type": null } }, { "pk": 11, "model": "sciblog.resultcontent", "fields": { "card_content": "", "blog": 3, "shorttitle": "", "abstract": "", "content": "<br data-mce-bogus=\"1\">", "sample": [], "indicators": [], "type": null } }, { "pk": 12, "model": "sciblog.resultcontent", "fields": { "card_content": "\u7a76\u540e\u9762\u7684\u6570\u636e\u663e\u793a\u8fd9\u53ea\u662f\u6682", "blog": 1, "shorttitle": "\u7a76\u540e\u9762\u7684\u6570\u636e\u663e\u793a\u8fd9\u53ea\u662f\u6682", "abstract": "", "content": "\u7a76\u540e\u9762\u7684\u6570\u636e\u663e\u793a\u8fd9\u53ea\u662f\u6682", "sample": [], "indicators": [], "type": 3 } }, { "pk": 1, "model": "sciblog.reference", "fields": { "link": "http://www.ncbi.nlm.nih.gov/pubmed/14697813", "description": "Lai CL, Ratziu V, Yuen MF, Poynard T. Viral hepatitis B. Lancet 2003;362:2089-94." } }, { "pk": 2, "model": "sciblog.reference", "fields": { "link": "http://onlinelibrary.wiley.com/doi/10.1002/hep.23722/full", "description": "Rijckborst V, Hansen BE, Cakaloglu Y, Ferenci P, Tabak F, Akdogan M, Simon K, Akarca US, Flisiak R, Verhey E, Van Vuuren AJ, Boucher CA, ter Borg MJ, Janssen HL. Early on-treatment prediction of response to peginterferon alfa-2a for HBeAg-negative chronic hepatitis B using HBsAg and HBV DNA levels.Hepatology. 2010 Aug;52(2):454-61. doi: 10.1002" } }, { "pk": 3, "model": "sciblog.reference", "fields": { "link": "", "description": "Hepatitis B surface antigen: association with sustained response to peginterferon alfa-2a in hepatitis B e antigen-positive patients\r\n" } }, { "pk": 1, "model": "sciblog.knowledgepiece", "fields": { "content": 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