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|
[
{
"pk": 1,
"model": "sciblog.sciblog",
"fields": {
"subhead": "\u5c0f\u4e09\u9633\u6162\u6027\u4e59\u809d\u60a3\u8005\u901a\u8fc7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\uff0c\u6216\u8005\u957f\u6548\u5e72\u6270\u7d20\uff0c\u6cbb\u7597\u7684\u6548\u679c\u5982\u4f55\uff1f\u526f\u4f5c\u7528\u662f\u5426\u5f88\u5927\uff1f\u548c\u62c9\u7c73\u592b\u5b9a\u76f8\u6bd4\u600e\u4e48\u6837\uff1f",
"sample": [],
"readed_count": 0,
"references": [],
"catched_by": [
1,
4
],
"query": [
72,
73,
74,
75
],
"endpoint_content": "",
"treatment_content": "\u6309\u71671\uff1a1\uff1a1\u5206\u7ec4\u3002\r\n\u7b2c\u4e00\u7ec4\uff1a\u5e72\u6270\u7d20\u5358\u836f\u7ec4\uff1a180ug\u6bcf\u5468\u4e00\u6b21\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\uff08\u6d3e\u7f57\u6b23\uff0c\u7f57\u6c0f\uff09\uff1b\r\n\u7b2c\u4e8c\u7ec4\uff1a\u5e72\u6270\u7d20\u62c9\u7c73\u592b\u5b9a\u8054\u7528\u7ec4\uff1a180ug\u6bcf\u5468\u4e00\u6b21\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\uff08\u6d3e\u7f57\u6b23\uff0c\u7f57\u6c0f\uff09\u7684\u540c\u65f6\u6bcf\u5929\u670d\u7528100mg\u62c9\u7c73\u592b\u5b9a\uff08 Epivir-HBV or Zeffix\uff0c\u845b\u5170\u7d20\u53f2\u514b\uff09\uff1b\r\n\u7b2c\u4e09\u7ec4\uff1a\u62c9\u7c73\u592b\u5b9a\u5358\u836f\u7ec4\uff1a\u6bcf\u5929\u670d\u7528100mg\u62c9\u7c73\u592b\u5b9a\uff08 Epivir-HBV or Zeffix\uff0c\u845b\u5170\u7d20\u53f2\u514b\uff09\r\n48\u5468\u7597\u7a0b\uff0c\u6cbb\u7597\u7ed3\u675f\u540e\u7ee7\u7eed\u968f\u8bbf\u89c2\u5bdf24\u5468\u3002",
"baseline": [],
"title": "\u5355\u7528\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u3001\u62c9\u7c73\u592b\u5b9a\u5355\u7528\u3001\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u4e0e\u62c9\u7c73\u592b\u5b9a\u8054\u5408\u7528\u836f\u5728\u6cbb\u7597e\u6297\u539f\u9634\u6027\u6162\u6027\u4e59\u809d\u65f6\u7684\u6548\u679c\u4e0e\u5b89\u5168\u6027",
"clinic_conditions": [
14
],
"hospital": [
1,
2,
3,
4
],
"source": null,
"understanded_count": 0,
"safety": "\u4f1a\u4e0d\u4f1a\u53d1\u751fYMDD\u53d8\u5f02\uff1f\r\n\u7ed3\u675f\u6cbb\u7597\u65f6\uff0cYMDD\u53d8\u5f02\u53d1\u751f\u7387\u5728\u62c9\u7c73\u592b\u5b9a\u7ec4\u91cc\u9762\u662f18%\uff0c\u5728\u5e72\u6270\u7d20+\u62c9\u7c73\u592b\u5b9a\u8054\u5408\u7ec4173\u540d\u60a3\u8005\u4e2d\uff0c\u53ea\u67091\u4f4d\u60a3\u8005\u53d1\u751fYMDD\u53d8\u5f02\u3002\r\n\r\n\u4e0d\u826f\u53cd\u5e94\u6709\u54ea\u4e9b\uff1f",
"entitle": "Peginterferon Alfa-2a Alone, Lamivudine Alone, and the Two in Combination in Patients with HBeAg-Negative Chronic Hepatitis B",
"konwledge_piece": [
1,
2,
3,
24
],
"method": "\u672c\u6587\u6d89\u53ca\u7684\u7814\u7a76\u662f\u968f\u673a\u3001\u90e8\u5206\u53cc\u76f2\u7814\u7a76\uff0c\u4ece\u5168\u7403\u591a\u4e2d\u5fc3\uff0813\u4e2a\u56fd\u5bb654\u4e2a\u4e2d\u5fc3\uff0c\u6709\u4e00\u90e8\u5206\u5728\u4e9a\u6d32\u548c\u6b27\u6d32\uff09\u62db\u52df\u60a3\u8005\u3002 \r\n\r\n\u7814\u7a76\u5206\u6790\u4e86\u4e09\u7ec4\u4eba\u7fa4\uff08\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u3001\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u4e0e\u62c9\u7c73\u592b\u5b9a\u8054\u5408\u7528\u836f\u3001\u62c9\u7c73\u592b\u5b9a\u5355\u836f\u6cbb\u7597\uff09\u7684\u6cbb\u7597\u540e\u60c5\u51b5\u3002\u4e09\u7ec4\u4eba\u7fa4\u90fd\u662f48\u5468\u7684\u6cbb\u7597\u7597\u7a0b\uff0c\u6cbb\u7597\u540e\u7814\u7a76\u4eba\u5458\u4f1a\u7ee7\u7eed\u968f\u8bbf\u8ddf\u8e2a24\u5468\u75c5\u60c5\u53d1\u5c55\u3002",
"conclusion": "e\u6297\u539f\u9634\u6027\u7684\u6162\u6027\u4e59\u809d\u60a3\u8005\u7684\u6301\u7eed\u5e94\u7b54\u7387\u5728\u542b\u6709\u5e72\u6270\u7d20\u7684\u6cbb\u7597\u7ec4\u4e2d\u7684\u60a3\u8005\u660e\u663e\u9ad8\u4e8e\u4ec5\u7528\u62c9\u7c73\u592b\u5b9a\u7684\u60a3\u8005\u3002\r\n\r\n\u6301\u7eed\u5e94\u7b54\u6307\u7684\u662f\u505c\u836f24\u5468\u5468\u540e\u4ecd\u6709\u5e94\u7b54\u3002\r\n\r\n\u5728\u5e72\u6270\u7d20\u7684\u6cbb\u7597\u57fa\u7840\u4e0a\u52a0\u4e0a\u62c9\u7c73\u592b\u5b9a\u8fdb\u884c\u8054\u5408\u4f5c\u7528\uff0c\u76f8\u5bf9\u4e8e\u53ea\u7528\u5e72\u6270\u7d20\u6cbb\u7597\u5e76\u6ca1\u6709\u63d0\u9ad8\u4ec0\u4e48\u6548\u679c\u3002",
"detectionAssay": "",
"ifvalue": 11.0,
"journal": "NEJM",
"authors": "Patrick Marcellin , M.D., George K.K. Lau, M.D., Ferruccio Bonino, M.D., Patrizia Farci, M.D., Stephanos Hadziyannis, M.D., Rui Jin, M.D., Zhi-Meng Lu, M.D., Teerha Piratvisuth, M.D., Georgios Germanidis, M.D., Cihan Yurdaydin, M.D., Moises Diago, M.D., Selim Gurel, M.D., Ming-Yang Lai, M.D., Peter Button, M.Sc., and Nigel Pluck, M.D., for the Peginterferon Alfa-2a HBeAg-Negative Chronic Hepatitis B Study Group",
"abstractAE": "\u5173\u4e8e\u4e0d\u826f\u53cd\u5e94\uff0c\u5305\u62ec\u53d1\u70ed\u3001\u4e4f\u529b\u3001\u808c\u75db\u3001\u5934\u75db\u5728\u5185\u7684\u4e0d\u826f\u53cd\u5e94\u5728\u542b\u6709\u5e72\u6270\u7d20\u7684\u6cbb\u7597\u7ec4\u4eba\u7fa4\u4e2d\u8981\u7a0d\u5fae\u5927\u4e00\u4e9b\u3002",
"confused_count": 0,
"collected_by": [
1,
4
],
"guidline": 1,
"aim": "<p class=\"highlight\">\u672c\u7814\u7a76\u6240\u89c2\u6d4b\u7684\u662f\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\uff08\u5355\u836f\u6cbb\u7597\u3001\u5e72\u6270\u7d20\u4e0e\u62c9\u7c73\u592b\u5b9a\u8054\u5408\u6cbb\u7597\u3001\u62c9\u7c73\u592b\u5b9a\u5355\u836f\u6cbb\u7597\u8fd93\u4e2d\u4e0d\u540c\u7684\u65b9\u6cd5\u6cbb\u7597e\u6297\u539f\uff08HBeAg\uff09\u9634\u6027\u6162\u6027\u4e59\u809d\u7684\u6548\u679c\u3001\u5b89\u5168\u6027\u3002</p>",
"publish_date": "2005-03-27",
"abstract_result": "24\u5468\u968f\u8bbf\u671f\u7ed3\u675f\u4ee5\u540e\uff0c\u8c37\u4e19\u8f6c\u6c28\u9176\uff08ALT\uff09\u7684\u590d\u5e38\u7387\uff08\u6062\u590d\u6b63\u5e38\u503c\u4ee5\u5185\u7684\u51e0\u7387\uff09\u6216\u8005\u4e59\u809d\u75c5\u6bd2\uff08HBV\uff09 DNA\u6c34\u5e73\u964d\u4f4e\u523020,000\u62f7\u8d1d/mL\u7684\u51e0\u7387\u5728\u63a5\u53d7\u542b\u6709\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\uff08 \u4e0b\u6587\u6b64\u7c7b\u5e72\u6270\u7d20\u90fd\u7b80\u79f0\u4e3a\u201c\u5e72\u6270\u7d20\u201d\uff0c\u5982\u6709\u8bf4\u5230\u666e\u901a\u5e72\u6270\u7d20\u4f1a\u7279\u522b\u6307\u51fa\uff09\u7684\u6cbb\u7597\u7ec4\u4eba\u7fa4\u4e2d\u4f1a\u66f4\u9ad8\uff08\u6bd4\u8d77\u90a3\u4e9b\u4ec5\u7528\u62c9\u7c73\u592b\u5b9a\u7684\u60a3\u8005\uff09\u3002\r\n\r\n\u5728\u7ed3\u675f\u6cbb\u759724\u5468\u540e\uff0c\u75c5\u6bd2\u6c34\u5e73\u964d\u5230400\u62f7\u8d1d/mL\u662f\u5f88\u591a\u4eba\u8ffd\u6c42\u7684\u6cbb\u7597\u7ec8\u70b9\uff0c\u5728\u542b\u6709\u5e72\u6270\u7d20\u7684\u6cbb\u7597\u7ec4\u4eba\u7fa4\u4e2d\u5927\u6982\u670920%\u5de6\u53f3\u83b7\u5f97\u4e86\u8fd9\u6837\u7684\u75c5\u6bd2\u5b66\u5e94\u7b54\uff0c\u4ec5\u7528\u62c9\u7c73\u592b\u5b9a\u7684\u60a3\u8005\u8fd9\u4e2a\u6570\u5b57\u53ea\u67097%\u3002\r\n\r\n\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u7684\u6e05\u9664\uff0c\u53ea\u670912\u4e2a\u4eba\u53d1\u751f\uff08\u90fd\u5728\u542b\u6709\u5e72\u6270\u7d20\u7684\u6cbb\u7597\u7ec4\u4eba\u7fa4\u4e2d\uff0c\u5360\u6bd43.4%\uff09\uff0c\u4ec5\u7528\u62c9\u7c73\u592b\u5b9a\u7684\u6cbb\u7597\u7ec4\u4e2d\u6ca1\u6709\u4eba\u83b7\u5f97HBsAg\u6e05\u9664\u3002",
"endpoints": [
1,
2,
3,
4,
5,
6
]
}
},
{
"pk": 2,
"model": "sciblog.sciblog",
"fields": {
"subhead": "HBeAg\u9634\u6027\u6162\u4e59\u809d\u60a3\u8005\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u6cbb\u7597\u65f6\uff0c\u65e9\u671f\u53ef\u4ee5\u901a\u8fc7HBsAg\u548cHBV DNA\u7684\u5b9a\u91cf\u6c34\u5e73\u6765\u9884\u6d4b\u4ee5\u540e\u7684\u5e94\u7b54\u6548\u679c",
"sample": [],
"readed_count": 0,
"references": [
2
],
"catched_by": [],
"query": [],
"endpoint_content": "\u672c\u7814\u7a76\u6839\u636e\u6b27\u6d32\u809d\u75c5\u534f\u4f1a\u6700\u65b0\u6307\u5357\u4e2d\u5bf9\u4e8e\u6cbb\u7597\u7ec8\u70b9\u4ee5\u53ca\uff08\u805a\u4e59\u4e8c\u9187\uff09\u5e72\u6270\u7d20\u6cbb\u7597\u7684\u75c5\u6bd2\u5b66\u5e94\u7b54\u7684\u5b9a\u4e49\u6765\u786e\u5b9a\u7814\u7a76\u7ec8\u70b9SR\u3002\u672c\u6587\u4e2d\uff0cHBeAg\u9634\u6027\u6162\u6027\u4e59\u809d\u60a3\u8005\u83b7\u5f97SR(sustained response\uff0c\u6301\u7eed\u5e94\u7b54\uff09\u662f\u6307\uff1a\r\n\u968f\u8bbf\u7ec8\u70b9\uff08\u7b2c72\u5468\uff09\u7684\u65f6\u5019\uff0cHBV DNA\u6c34\u5e73\u5c0f\u4e8e10000\u62f7\u8d1d/ml\uff08\u76f8\u5f53\u4e8e1714 IU/mL \uff09\r\n\u968f\u8bbf\u7ec8\u70b9\uff08\u7b2c72\u5468\uff09\u7684\u65f6\u5019\uff0cALT\u6062\u590d\u6b63\u5e38",
"treatment_content": "\u60a3\u8005\u6309\u71671\uff1a1\u6bd4\u4f8b\u88ab\u968f\u673a\u5206\u914d\u5230\u4e24\u7ec4\u4eba\u5f53\u4e2d\uff0c\u4e00\u7ec4\u63a5\u53d7180ug/\u6bcf\u5468\u7684\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u8054\u5408\u5229\u5df4\u97e6\u67971000mg/\u6bcf\u5929\uff08\u4f53\u91cd\u5c0f\u4e8e75\u5343\u514b\uff09\u6216\u80051200mg/\u6bcf\u5929\uff08\u4f53\u91cd>=75\u5343\u514b\u7684\uff09\u6cbb\u7597\uff0c\u8fd8\u6709\u4e00\u7ec4\u662f\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20180ug/\u6bcf\u5468\u7684\u5358\u836f\u6cbb\u7597\u3002\r\n\r\n48\u5468\u7597\u7a0b\uff0c\u6cbb\u7597\u7ed3\u675f\u540e\u7ee7\u7eed\u968f\u8bbf\u89c2\u5bdf24\u5468\u3002\r\n\r\n\u75c5\u60a3\u6bcf\u4e2a\u6708\u53c2\u52a0\u4e00\u6b21\u95e8\u8bca\u3002\r\n\r\n\u8868\u9762\u6297\u539f\u5b9a\u91cf\u68c0\u6d4b\u65f6\u95f4\u70b9\uff1a\u6cbb\u7597\u671f\u95f4\u7b2c4\u30018\u300112\u300124\u300136\u300148\u5468\uff0c\u968f\u8bbf\u671f\u95f4\u7b2c60\u300172\u5468\u3002",
"baseline": [],
"title": "HBeAg\u9634\u6027\u6162\u4e59\u809d\u60a3\u8005\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u6cbb\u7597\u65f6\uff0c\u65e9\u671f\u53ef\u4ee5\u901a\u8fc7HBsAg\u548cHBV DNA\u7684\u5b9a\u91cf\u6c34\u5e73\u6765\u9884\u6d4b\u4ee5\u540e\u7684\u5e94\u7b54\u6548\u679c",
"clinic_conditions": [
13,
14,
15,
16,
17,
18,
19,
20,
21
],
"hospital": [],
"source": null,
"understanded_count": 0,
"safety": "",
"entitle": "Early on-treatment prediction of response to peginterferon alfa-2a for hbeag-negative chronic hepatitis b using hbsag and hbv dna levels",
"konwledge_piece": [
4,
5,
6,
7,
8,
9,
10,
11,
12,
13,
14,
15,
16
],
"method": "\u672c\u7814\u7a76\u60a3\u8005\u90fd\u662f\u63a5\u53d7PEG\u5e72\u6270\u7d20\u6cbb\u7597\u3002",
"conclusion": "\u9488\u5bf9\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6cbb\u7597\u7684HBeAg\u9634\u6027\u6162\u4e59\u809d\u60a3\u8005\uff0c\u672c\u7814\u7a76\u5b66\u8005\u5efa\u8bae\u4e86\u4e00\u4e2a\u5728\u6cbb\u7597\u5f00\u59cb\u540e\u7b2c12\u5468\u65f6\u5224\u65ad\u662f\u5426\u9700\u8981\u505c\u836f\u7684\u51c6\u5219\uff0c\u8fd9\u4e2a\u51c6\u5219\u57fa\u4e8e\u8840\u6e05\u4e2dHBV DNA\u548cHBsAg\u4e24\u4e2a\u6307\u6807\u4ece\u57fa\u7ebf\u5f00\u59cb\u7684\u4e0b\u964d\u6c34\u5e73\u3002\u6362\u8a00\u4e4b\uff0c\u4e34\u5e8a\u4e2d\uff0c\u540c\u65f6\u5b9a\u91cf\u68c0\u6d4bHBsAg\u548cHBV DNA\u80fd\u591f\u8c03\u6574\u805a\u4e59\u4e8c\u9187\u6cbb\u7597HBeAg\u9634\u6027\u6162\u4e59\u809d\u7684\u7b56\u7565\u3002\r\n\r\n\u5bf9\u4e8e\u4ee5\u4e0b\u60a3\u8005\uff1a\u6cbb\u7597\u7b2c12\u5468\u65f6\uff0c\u76f8\u6bd4\u57fa\u7ebf\uff08\u6cbb\u7597\u5f00\u59cb\uff09\uff0c\u8840\u6e05HBsAg\u6c34\u5e73\u6ca1\u6709\u4e0b\u964d\u800c\u4e14HBV DNA \u4e0b\u964d<2 log \u62f7\u8d1d/mL \uff0c\u5e94\u8be5\u505c\u6b62\u5e72\u6270\u7d20\u7684\u6cbb\u7597\uff0c\u6362\u7528\u5176\u4ed6\u6cbb\u7597\u65b9\u6cd5\u3002",
"detectionAssay": "\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u5b9a\u91cf\u68c0\u6d4b\uff1a\u96c5\u57f9 Architect HBsAg assay (Abbott Laboratories\uff09\u63d0\u4f9b\uff0c \u7ebf\u6027\u8303\u56f4\u662f0.05-250 IU/mL\r\n\u4e59\u809d\u75c5\u6bd2\uff08HBV DNA\uff09\u68c0\u6d4b\uff1a\u7f57\u6c0f\u8bca\u65ad TaqMan HBV assay, Roche Diagnostics\u63d0\u4f9b\uff0c\u68c0\u6d4b\u4e0b\u965035copies/mL\r\n\u8c37\u4e19\u8f6c\u6c28\u9176\uff08ALT\uff09\u68c0\u6d4b\uff1a\u5728\u7814\u7a76\u5f53\u5730\u533b\u9662\u6309\u7167\u6807\u51c6\u64cd\u4f5c\r\n\u4e59\u809d\u75c5\u6bd2\uff08HBV\uff09\u57fa\u56e0\u578b\u68c0\u6d4b\uff1a INNO-LiPA assay (Innogenetics)\r\n\u809d\u7a7f\u523a\u68c0\u6d4b\uff1a\u6bcf\u4e2a\u60a3\u8005\u90fd\u6709\u5165\u7ec4\u524d\u4e00\u5e74\u5185\u7684\u809d\u7a7f\u7ed3\u679c\uff0c\u7528Ishak\u8bc4\u5206\u7cfb\u7edf\u6765\u8868\u793a\u809d\u810f\u708e\u75c7\u7684\u7b49\u7ea7\uff080-18\u5206\uff09\u548c\u809d\u810f\u7ea4\u7ef4\u5316\u7684\u7a0b\u5ea6\uff080-6\u5206\uff09",
"ifvalue": 11.0,
"journal": "Hepatology",
"authors": "Harry Janssen , Vincent Rijckborst\uff0cBettina E. Hansen, Yilmaz Cakaloglu, Peter Ferenci, Fehmi Tabak, Meral Akdogan, Krzysztof Simon, Ulus S. Akarca, Robert Flisiak, Elke Verhey, Anneke J. Van Vuuren, Charles A. B. Boucher, Martijn J. ter Borg Harry L. A. Janssen ",
"abstractAE": "",
"confused_count": 0,
"collected_by": [],
"guidline": null,
"aim": "\u8fd9\u9879\u7814\u7a76\u662f\u7814\u7a76\u8005\u4e3b\u5bfc\u578b\u3001\u591a\u4e2d\u5fc3\u3001\u968f\u673a\u3001\u53cc\u76f2\u3001\u5bf9\u7167\u7814\u7a76\uff0c\u8be5\u7814\u7a76\u9075\u5b88\u8d6b\u5c14\u8f9b\u57fa\u5ba3\u8a00\u3002\r\n1.\u7814\u7a76\u7684\u76ee\u7684\u662f\u4e3a\u5f04\u6e05\u695a\u5728\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alpha-2a\u6cbb\u7597\u7684e\u6297\u539f\u9634\u6027\u6162\u4e59\u809d\u60a3\u8005\u4e2d\uff0c\u6cbb\u7597\u524d\u671f\u5b9a\u91cf\u7684\u8840\u6e05HBsAg\u542b\u91cf\u5728\u9884\u6d4b\u4eca\u540e\u6301\u7eed\u5e94\u7b54\u6548\u5e94\u65f6\u7684\u4f5c\u7528\u3002\r\n2. \u9488\u5bf9\u8fd9\u90e8\u5206\u60a3\u8005\u6765\u627e\u5230\u53ef\u9760\u7684\u6cbb\u7597\u6307\u5357\u65b9\u9488\u6765\u6307\u5bfc\u505c\u836f\u3002",
"publish_date": "2010-04-19",
"abstract_result": "\u56de\u987e\u8be5\u7814\u7a76\u4e2d\u7684\u6301\u7eed\u5e94\u7b54\u8005\u5728\u6cbb\u7597\u671f\u95f4\u7684\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u6c34\u5e73\u7684\u53d8\u5316\uff0c\u4ece\u6cbb\u75978\u5468\u5f00\u59cb\uff0c\u8fd9\u4e9b\u5e94\u7b54\u8005\u7684HBsAg\u7684\u6c34\u5e73\u660e\u663e\u4e0b\u964d\uff1b\u76f8\u53cd\uff0c\u7ed3\u675f\u6cbb\u7597\u540e\u6ca1\u6709\u53d1\u751f\u6301\u7eed\u5e94\u7b54\u7684\u60a3\u8005\u6cbb\u7597\u671f\u95f4HBsAg\u6c34\u5e73\u53ea\u6709\u8f7b\u5fae\u7684\u4e0b\u964d\u3002\r\n\r\n\u6839\u636e\u7edf\u8ba1\u5b66\u5904\u7406\uff0c\u6216\u8005\u8bf4\u901a\u8fc7\u53d7\u8bd5\u8005\u5de5\u4f5c\u66f2\u7ebf\u7684AUC\u5224\u65ad\uff0c\u4ec5\u4ec5\u4f9d\u9760HBsAg\u7684\u4e0b\u964d\u9884\u6d4b\u6301\u7eed\u5e94\u7b54\u6709\u9650\u5236\u3002\r\n\r\n\u628aHBsAg\u4e0b\u964d\u548c\u4e59\u809d\u75c5\u6bd2\uff08HBV DNA\uff09\u4e0b\u964d\u7ed3\u5408\u8d77\u6765\u80fd\u591f\u6700\u597d\u5730\u9884\u6d4b\u6301\u7eed\u5e94\u7b54\u3002\r\n\r\n\u672c\u6587\u88ab\u89c2\u5bdf\u7684\u901a\u8fc7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6cbb\u7597\u7684e\u6297\u539f\u9634\u6027\u6162\u4e59\u809d\u60a3\u8005\u4e2d\uff0c\u6cbb\u7597\u671f\u95f4HBsAg\u6ca1\u6709\u51fa\u73b0\u4e0b\u964d\u5e76\u4e14DNA\u6c34\u5e73\u4e0b\u964d\u5c0f\u4e8e2\u4e2alog \u62f7\u8d1d/ml\u7684\u4eba\uff0c\u6cbb\u7597\u7ed3\u675f\u540e\u90fd\u6ca1\u6709\u51fa\u73b0\u6301\u7eed\u5e94\u7b54\uff0c\u8fd9\u90e8\u5206\u60a3\u8005\u5360\u672c\u6587\u88ab\u89c2\u5bdf\u60a3\u800520%\u3002\r\n\r\n\u76f8\u53cd\uff0c\u5982\u679c12\u5468\u540c\u65f6\u51fa\u73b0HBsAg\u4e0b\u964d\u4ee5\u53caDNA\u6c34\u5e73\u4e0b\u964d\u5927\u4e8e2\u4e2alog \u62f7\u8d1d/ml\u60a3\u8005\u6700\u7ec8\u51fa\u73b0\u6301\u7eed\u5e94\u7b54\u7684\u51e0\u7387\u4e3a39%\uff08\u76f8\u5bf9\u672c\u7814\u7a76\u5176\u4ed6\u7ec4\u522b\u6700\u9ad8\uff09\uff0c\u8fd9\u90e8\u5206\u60a3\u8005\u5360\u672c\u7814\u7a76\u6574\u4e2a\u4eba\u7fa427%\u3002",
"endpoints": [
1,
7
]
}
},
{
"pk": 3,
"model": "sciblog.sciblog",
"fields": {
"subhead": "\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u6cbb\u7597e\u6297\u539f\u9633\u6027\u6162\u6027\u4e59\u809d\uff0c\u8868\u9762\u6297\u539f\u6cbb\u7597\u671f\u95f412\u5468\u300124\u5468\u6c34\u5e73\u53ef\u80fd\u9884\u793a\u6301\u4e45\u5e94\u7b54",
"sample": [],
"readed_count": 0,
"references": [
3
],
"catched_by": [
1
],
"query": [],
"endpoint_content": "\u672c\u6587\u6cbb\u7597\u5e94\u7b54\u5b9a\u4e49\u4e3a\uff1a\u6cbb\u7597\u7ed3\u675f6\u4e2a\u6708\u540ee\u6297\u539f\uff08HBeAg\uff09\u53d1\u751f\u8840\u6e05\u5b66\u8f6c\u6362\u3002",
"treatment_content": "\u88ab\u7814\u7a76\u8005\uff08399\u4eba\uff09\u4e2d\uff0c \u4e00\u534a\u4eba\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6cbb\u7597\uff08\u6bcf\u5468180ug\uff09\uff0c\u53e6\u4e00\u534a\u4eba\u63a5\u53d7\u8054\u5408\u6cbb\u7597\uff0c\u5373\u5728\u7b2c\u4e00\u7ec4\u6cbb\u7597\u65b9\u6848\u7684\u57fa\u7840\u4e0a\u518d\u52a0\u7528\u62c9\u7c73\u592b\u5b9a\uff08\u6bcf\u5929100mg\uff09\uff0c\u4e24\u7ec4\u6cbb\u7597\u90fd\u662f\u6301\u7eed48\u5468\u3002\r\n\u968f\u8bbf\u65f6\u95f4\u70b9\uff1a\u57fa\u7ebf\uff08\u6cbb\u7597\u5f00\u59cb\uff09\u3001\u6cbb\u7597\u5f00\u59cb\u540e12\u5468\uff0c24\u5468\uff0c48\u5468\uff08\u6cbb\u7597\u7ed3\u675f\uff09",
"baseline": [],
"title": "[\u56de\u987e\u6027\u5206\u6790]\u8868\u9762\u6297\u539f\u4e0e\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u6cbb\u7597e\u6297\u539f\u9633\u6027\u6162\u4e59\u809d\u60a3\u8005\u6301\u4e45\u5e94\u7b54\u7684\u5173\u7cfb",
"clinic_conditions": [],
"hospital": [
4,
5,
6
],
"source": null,
"understanded_count": 0,
"safety": "",
"entitle": "Hepatitis B surface antigen: association with sustained response to peginterferon alfa-2a in hepatitis B e antigen-positive patients",
"konwledge_piece": [
17,
18,
19,
20,
21,
22,
23
],
"method": "\u672c\u7814\u7a76\u662f\u9488\u5bf9\u4e00\u4e2a\u5927\u578b\u7684\u3001\u968f\u673a\u7814\u7a76\u7684\u56de\u987e\u6027\u5206\u6790\u3002\u56e0\u4e3a\u672c\u6587\u8981\u89c2\u5bdf\u60a3\u8005\u5728\u6cbb\u7597\u671f\u95f4\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u7684\u53d8\u5316\uff0c\u6240\u4ee5\u56de\u987e\u91c7\u7528\u7684\u90fd\u662f\u4fdd\u7559\u6709\u8868\u9762\u6297\u539f\u968f\u8bbf\u8bb0\u5f55\u7684\u60a3\u8005\u7684\u6570\u636e\uff0c\u539f\u6765\u7684\u5927\u578b\u7814\u7a76\u6709542\u4eba\uff0c\u672c\u6587\u5206\u6790\u7528\u5230\u7684\u6570\u636e\u6709399\u4eba\u3002\u8fd9399\u4eba\u4e2d\uff0c\u4e00\u534a\u4eba\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u6cbb\u7597\uff08\u6bcf\u5468180ug\uff09\uff0c\u53e6\u4e00\u534a\u4eba\u63a5\u53d7\u8054\u5408\u6cbb\u7597\uff0c\u5c31\u662f\u5728\u7b2c\u4e00\u7ec4\u6cbb\u7597\u65b9\u6848\u7684\u57fa\u7840\u4e0a\u518d\u52a0\u7528\u62c9\u7c73\u592b\u5b9a\uff08\u6bcf\u5929100mg\uff09\uff0c\u4e24\u7ec4\u6cbb\u7597\u90fd\u662f\u6301\u7eed48\u5468\u3002",
"conclusion": "\u901a\u8fc7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u6cbb\u7597e\u6297\u539f\uff08HBeAg\uff09\u9633\u6027\u6162\u4e59\u809d\u60a3\u8005\u7684\u65f6\u5019\uff0c\u6cbb\u7597\u671f\u95f4\u8840\u6e05\u4e2d\u8868\u9762\u6297\u539f\u7684\u6c34\u5e73\u4e0e\u6cbb\u7597\u7ed3\u675f\u540e\u6301\u4e45\u5e94\u7b54\u6709\u5173\u8054\u3002\u57fa\u7ebf\u8868\u9762\u6297\u539f\u6c34\u5e73\u548c\u6301\u4e45\u5e94\u7b54\u662f\u5426\u6709\u5173\u7cfb\u672c\u7814\u7a76\u4e0d\u8db3\u4ee5\u8bc1\u5b9e\u3002\u4f46\u5b9a\u91cf\u68c0\u6d4b\u8868\u9762\u6297\u539f\u6216\u8bb8\u53ef\u4ee5\u5e2e\u52a9\u60a3\u8005\u6307\u5bfc\u4eca\u540e\u7684\u6cbb\u7597\u65b9\u6848\u3002[2]",
"detectionAssay": "\u8868\u9762\u6297\u539f(HBsAg)\u6c34\u5e73\u7684\u5b9a\u91cf\u68c0\u6d4b\uff1a Abbott Architect HBsAg assay (Abbott Laboratories, IL, USA\uff09\r\nHBV DNA\u6c34\u5e73\u68c0\u6d4b\uff1a Amplicor HBV test (\u7f57\u6c0f\u5206\u5b50\u8bca\u65ad Roche Molecular Diagnostics, Pleasanton, CA, USA\uff09",
"ifvalue": 2.6,
"journal": "Hepatol Int. ",
"authors": "default authors",
"abstractAE": "<br data-mce-bogus=\"1\">",
"confused_count": 0,
"collected_by": [
1,
2
],
"guidline": null,
"aim": "\u5728\u4f7f\u7528\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u8fdb\u884c\u6cbb\u7597e\u6297\u539f\uff08HBeAg\uff09\u9633\u6027\u6162\u6027\u4e59\u578b\u809d\u708e\u7684\u65f6\u5019\uff0c\u6cbb\u7597\u7ed3\u675f\u540e6\u4e2a\u6708\u5982\u679c\u53d1\u751fe\u6297\u539f\u8840\u6e05\u5b66\u8f6c\u6362\uff0c\u90a3\u5c31\u9884\u793a\u7740\u505c\u836f\u540e\u957f\u671f\u968f\u8bbf\u671f\u95f4\u8868\u9762\u6297\u539f\u7684\u6e05\u9664\u7387\u4f1a\u63d0\u9ad8\u3002\u800c\u672c\u6587\u5b66\u8005\u628a\u5173\u6ce8\u70b9\u653e\u5728\u4e86\u53e6\u4e00\u4e2a\u6307\u6807--\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u4e0a\uff0c\u6240\u7814\u7a76\u7684\u8bdd\u9898\u662f\u5728\u6cbb\u7597\u671f\u95f4\u7684\u65f6\u5019\u901a\u8fc7\u5b9a\u91cf\u68c0\u6d4b\u8868\u9762\u6297\u539f\u80fd\u5426\u4e5f\u53ef\u4ee5\u9884\u6d4b\u6cbb\u7597\u7ed3\u675f\u540e\u7684\u5e94\u7b54\u3002",
"publish_date": "2011-01-05",
"abstract_result": "\u6cbb\u7597\u7ed3\u675f\u540e\u83b7\u5f97\u6cbb\u7597\u5e94\u7b54\u7684\u60a3\u8005\u57fa\u7ebf\u65f6\u8868\u9762\u6297\u539f\u7684\u6c34\u5e73\uff0c\u6bd4\u8d77\u90a3\u4e9b\u6ca1\u6709\u83b7\u5f97\u5e94\u7b54\u7684\u60a3\u8005\u7684\u57fa\u7ebf\u8868\u9762\u6297\u539f\u6c34\u5e73\u8981\u4f4e\u3002\uff083.97 log10 IU/mL \u6bd4 4.21 log10IU/mL\uff09\u3002\u5e76\u4e14\u83b7\u5f97\u5e94\u7b54\u7684\u60a3\u8005\u5728\u6574\u4e2a\u6cbb\u7597\u671f\u95f4>\u9762\u6297\u539f\uff08HBsAg\uff09\u4e0b\u964d\u7a0b\u5ea6\u66f4\u5927\u3002\r\n\u5728\u6cbb\u7597\u5f00\u59cb\u540e\u7b2c12\u5468\u8868\u9762\u6297\u539f\u7684\u503c\u4e0b\u964d\u52301,500IU/mL\u4ee5\u4e0b\u7684\u60a3\u8005\uff0c\u6cbb\u7597\u7ed3\u675f\u540ee\u6297\u539f\uff08HBeAg\uff09\u8840\u6e05\u5b66\u8f6c\u6362\u7387\u4e3a56.7%\uff1b \r\n\u572824\u5468\u8868\u9762\u6297\u539f\u7684\u503c\u4e0b\u964d\u52301,500IU/mL\u4ee5\u4e0b\u7684\u60a3\u8005\uff0c\u6cbb\u7597\u7ed3\u675f\u540ee\u6297\u539f\uff08HBeAg\uff09\u8840\u6e05\u5b66\u8f6c\u6362\u7387\u4e3a54.4%\u3002\u5982\u679c\u5728\u6cbb\u7597\u5f00\u59cb\u540e12\u5468\u6216\u800524\u5468\uff0c\u8868\u9762\u6297\u539f\uff08HBsAg\uff09\u6d4b\u5f97\u66f4\u9ad8\u7684\u503c\uff0c\u6bd4\u59821,500\u523020,000IU/mL\u6216\u8005\u5927\u4e8e20,000IU/mL\uff0c\u90a3\u4e48\u6cbb\u7597\u540e\u83b7\u5f97e\u6297\u539f\u8840\u6e05\u5b66\u8f6c\u6362\u7684\u51e0\u7387\u8981\u66f4\u4f4e\u3002\uff08\u524d\u8005\u4e3a32.3%\uff0c\u540e\u8005\u4e3a15.4%\uff09",
"endpoints": [
8,
9,
10
]
}
},
{
"pk": 4,
"model": "sciblog.sciblog",
"fields": {
"subhead": "e\u6297\u539f\u9633\u6027\u6162\u4e59\u809d\u60a3\u8005\u63a5\u53d7\u805a\u4e8c\u4e59\u9187\u5e72\u6270\u7d20alfa\u6cbb\u7597\u524d\u54ea\u4e9b\u8d77\u59cb\u56e0\u7d20\u53ef\u4ee5\u9884\u6d4b\u672a\u6765\u7597\u6548\u597d\u4e0e\u574f",
"sample": [],
"readed_count": 0,
"references": [],
"catched_by": [],
"query": [],
"endpoint_content": "",
"treatment_content": "\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa\u6cbb\u7597\u7684e\u6297\u539f\u6162\u4e59\u809d\u60a3\u8005\u4e2d\u6700\u6709\u53ef\u80fd\u83b7\u5f97\u6301\u4e45\u5e94\u7b54\u7684\u4eba\u6709\uff1a\r\n<ul><li>\u57fa\u7ebf\u9ad8\u8c37\u4e19\u8f6c\u6c28\u9176\u6c34\u5e73\u6216\u8005\u4f4eHBV DNA\u6c34\u5e73\u7684HBV\u57fa\u56e0\u578b\u4e3aA\u578b\u7684\u60a3\u8005\uff1b</li>\r\n<li>\u57fa\u7ebf\u9ad8\u8c37\u4e19\u8f6c\u6c28\u9176\u6c34\u5e73\u4e14HBV DNA\u4f4e\u6c34\u5e73\u7684B\u3001C\u578b\u60a3\u8005\u3002</li></ul>\r\nD\u578b\u60a3\u8005\u83b7\u5f97\u6301\u4e45\u5e94\u7b54\u7684\u51e0\u7387\u4f4e\u3002\r\n\u8be5\u7814\u7a76\u63d0\u4f9b\u4e86\u4e00\u4e2a\u5de5\u5177\u6765\u8ba1\u7b97\u901a\u8fc7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6cbb\u7597e\u6297\u539f\uff08HBeAg\uff09\u9633\u6027\u60a3\u8005\u83b7\u5f97\u6301\u7eed\u5e94\u7b54\u7684\u51e0\u7387\u3002\u7814\u7a76\u5efa\u8bae\u4e86\u51e0\u4e2a\u91cd\u8981\u7684\u4eba\u7fa4\u5e94\u8be5\u8003\u8651\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6cbb\u7597\u3002\r\n",
"baseline": [],
"title": "\u80fd\u591f\u9884\u6d4b\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa\u6cbb\u7597e\u6297\u539f\u9633\u6027\u6162\u6027\u4e59\u578b\u809d\u708e\u5e94\u7b54\u7ed3\u679c\u7684\u56e0\u5b50",
"clinic_conditions": [],
"hospital": [
7
],
"source": null,
"understanded_count": 0,
"safety": "",
"entitle": "Factors That Predict Response of Patients With Hepatitis B e Antigen\u2013Positive Chronic Hepatitis B to Peginterferon-Alfa",
"konwledge_piece": [
25,
26,
27,
28
],
"method": "\u8be5\u7814\u7a76\u4e2d\u6709542\u4f4d\u60a3\u8005\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\u6bcf\u5468180ug\u957f\u8fbe48\u5468\u7684\u6cbb\u7597\uff0c\u53e6\u5916\u6709266\u4f4d\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2b\u6bcf\u5468100ug\u957f\u8fbe52\u5468\u7684\u6cbb\u7597\u3002\u6700\u7ec8\u62ff\u6765\u505a\u6570\u636e\u5206\u6790\u7684\u60a3\u8005\u6709721\u4f4d\uff08\u7531\u4e8e\u6570\u636e\u7f3a\u5931\u7b49\u5ba2\u89c2\u539f\u56e0\uff09\u3002\u53e6\u5916\u79d1\u7814\u4e2d\u5e38\u7528\u7684\u6570\u7406\u7edf\u8ba1\u65b9\u6cd5\u8bf8\u5982\u903b\u8f91\u56de\u5f52\u5206\u6790\u65b9\u6cd5\u7528\u6765\u8bc1\u5b9e\u6301\u4e45\u5e94\u7b54\u7684\u56e0\u5b50\uff0c\u4ece\u800c\u8be5\u7814\u7a76\u8fd8\u5efa\u7acb\u4e86\u591a\u53d8\u91cf\u7684\u9884\u6d4b\u7597\u6548\u7684\u6570\u5b66\u6a21\u578b\uff0c\u8fd9\u662f\u672c\u6587\u6700\u5927\u7684\u4eae\u70b9\u3002",
"conclusion": "\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa\u6cbb\u7597\u7684e\u6297\u539f\u6162\u4e59\u809d\u60a3\u8005\u4e2d\u6700\u6709\u53ef\u80fd\u83b7\u5f97\u6301\u4e45\u5e94\u7b54\u7684\u4eba\u6709\uff1a\r\n<ul><li>\u57fa\u7ebf\u9ad8\u8c37\u4e19\u8f6c\u6c28\u9176\u6c34\u5e73\u6216\u8005\u4f4eHBV DNA\u6c34\u5e73\u7684HBV\u57fa\u56e0\u578b\u4e3aA\u578b\u7684\u60a3\u8005\uff1b</li>\r\n<li>\u57fa\u7ebf\u9ad8\u8c37\u4e19\u8f6c\u6c28\u9176\u6c34\u5e73\u4e14HBV DNA\u4f4e\u6c34\u5e73\u7684B\u3001C\u578b\u60a3\u8005\u3002</li></ul>\r\nD\u578b\u60a3\u8005\u83b7\u5f97\u6301\u4e45\u5e94\u7b54\u7684\u51e0\u7387\u4f4e\u3002",
"detectionAssay": "",
"ifvalue": 11.68,
"journal": "Gastroenterology",
"authors": "Harry Janssen , Erik H.C.J.\u00a0Buster, Bettina E.\u00a0Hansen, George K.K.\u00a0Lau, Teerha\u00a0Piratvisuth, Stefan\u00a0Zeuzem, Ewout W.\u00a0Steyerberg",
"abstractAE": "\u672c\u6587\u672a\u6d89\u53ca\u526f\u4f5c\u7528\u7684\u8be6\u7ec6\u8ba8\u8bba\u3002",
"confused_count": 0,
"collected_by": [],
"guidline": null,
"aim": "\u901a\u8fc7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa\u6cbb\u7597\u6162\u4e59\u809d\u80fd\u591f\u5728\u5c11\u90e8\u5206\u4eba\u8eab\u4e0a\u8fbe\u5230\u6301\u7eed\u6027\u7684\u5e94\u7b54\uff0c\u800c\u4e14\u4e5f\u6709\u76f8\u5f53\u7684\u526f\u4f5c\u7528\u3002\u672c\u6587\u5206\u6790\u4e862\u4e2a\u6700\u5927\u7684\u5173<div class=\"image-wrap\">\r\n\t<a href=\"http://image.97suifang.com/media/imgs/2013/07/21/23-%E8%A1%A81_2.jpg\" class=\"enlarge-image\">\r\n\t\t<img src=\"http://image.97suifang.com/media/imgs/2013/07/21/22-%E8%A1%A83-1_4.jpg\" alt=\"\">\r\n\t</a>\r\n</div>\u4e8ee\u6297\u539f\u9633\u6027\u6162\u4e59\u809d\u7684\u5168\u7403\u4e34\u5e8a\u5b9e\u9a8c\uff0c\u6765\u786e\u5b9a\u54ea\u4e9b\u4eba\u6700\u5bb9\u6613\u5bf9\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20-alfa\u7684\u6cbb\u7597\u4ea7\u751f\u5e94\u7b54\u3002",
"publish_date": "2009-12-01",
"abstract_result": "<ol><li>HBV\u57fa\u56e0\u578b</li></ol>\u3001\u57fa\u7ebf\u9ad8\u6c34\u5e73\u7684\u8c37\u4e19\u8f6c\u6c28\u9176\uff08ALT\uff09\u6c34\u5e73\uff08>2\u4e2a\u6b63\u5e38\u503c\u4e0a\u9650\uff09\u3001\u57fa\u7ebf\u4f4e\u6c34\u5e73\u7684HBV DNA\uff08<2.0*10^8IU/mL\uff09\u3001\u5973\u6027\u3001\u5e74\u957f\u3001\u4ee5\u524d\u6ca1\u6709\u63a5\u53d7\u8fc7\u5e72\u6270\u7d20\u6cbb\u7597\u8fd9\u4e9b\u56e0\u7d20\u90fd\u80fd\u591f\u9884\u6d4b\u6301\u4e45\u5e94\u7b54\u3002\r\n\u4e59\u809d\u75c5\u6bd2\uff08HBV\uff09\u57fa\u56e0\u578bA\u578b\u3001\u57fa\u7ebf\u9ad8ALT\u503c\u548c/\u6216\u8005\u4f4eHBV-DNA\u6c34\u5e73\u7684\u60a3\u8005\u6709\u9ad8\u51e0\u7387\u83b7\u5f97\u6301\u4e45\u5e94\u7b54\uff08\u8d85\u8fc730%\uff09\u3002\r\n<p>\u4e0a\u8ff0\u8fd9\u4e9b\u56e0\u7d20\u4e2d\u6700\u5f3a\u7684\u9884\u6d4b\u56e0\u5b50\u662f\u57fa\u7ebf\u9ad8\u6c34\u5e73\u7684\u8c37\u4e19\u8f6c\u6c28\u9176\uff08\u5bf9\u4e8eHBV\u57fa\u56e0\u578bB\u578b\u60a3\u8005\uff09\u548c\u57fa\u7ebf\u4f4e\u6c34\u5e73\u7684HBV-DNA\uff08\u5bf9\u4e8eHBV\u57fa\u56e0\u578bC\u578b\u60a3\u8005\uff09\u3002\u57fa\u56e0\u578bD\u578b\u7684\u60a3\u8005\u83b7\u5f97\u6301\u4e45\u5e94\u7b54\u7684\u51e0\u7387\u4f4e\u3002</p>",
"endpoints": []
}
},
{
"pk": 1,
"model": "sciblog.resultcontent",
"fields": {
"card_content": "\u8be5\u7814\u7a76\u6240\u6709\u60a3\u8005\r\n",
"blog": 1,
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"type": 0,
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}
},
{
"pk": 3,
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"content": "\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20alfa-2a\uff0c\u5728\u666e\u901a\u5e72\u6270\u7d20\u7684\u57fa\u7840\u4e0a\u52a0\u4e0a40KD\u805a\u4e59\u4e8c\u9187\u9ad8\u5206\u5b50\u7269\u8d28\u5f62\u6210\u65b0\u7684\u836f\u7269\u3002\u5b83\u6bcf\u5468\u53ea\u9700\u4e00\u6b21\u4f7f\u7528\uff0c\u975e\u5e38\u65b9\u4fbf\uff0c\u80fd\u591f\u5728\u7528\u836f\u95f4\u9694\u671f\u5185\u6709\u6548\u5730\u4fdd\u6301\u4f53\u5185\u7684\u8840\u836f\u6d53\u5ea6\u3002\u5728\u4f5c\u7528\u673a\u7406\u4e0a\uff0c\u548c\u666e\u901a\u5e72\u6270\u7d20\u7c7b\u4f3c\uff0c\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u80fd\u591f\u6709\u514d\u75ab\u63d0\u54e6\u554a\u63a5\u548c\u6297\u75c5\u6bd2\u7684\u53cc\u91cd\u8c03\u8282\u4f5c\u7528\uff1b\u4f46\u662f\u76f8\u6bd4\u666e\u901a\u5e72\u6270\u7d20\uff0c\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6709\u66f4\u597d\u7684\u4e34\u5e8a\u6cbb\u7597\u6548\u679c\u3002",
"type": 0,
"title": ""
}
},
{
"pk": 4,
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"fields": {
"content": "HBeAg\u9634\u6027\u6162\u6027\u4e59\u578b\u809d\u708e\uff08CHB\uff09\u4ee3\u8868\u7740\u6574\u4e2a\u75c5\u6bd2\u611f\u67d3\u7684\u540e\u671f\u3002",
"type": 0,
"title": ""
}
},
{
"pk": 5,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u56e0\u4e3a\u60a3\u6709\u8fd9\u7c7b\u809d\u708e\u7684\u60a3\u8005\u81ea\u7136\u7f13\u89e3\u5f88\u5c11\u53d1\u751f\uff0c\u6240\u4ee5\u836f\u7269\u6cbb\u7597\u7ecf\u5e38\u88ab\u8fd0\u7528\u5728\u4ed6\u4eec\u8eab\u4e0a\uff0c\u800c\u4e14e\u6297\u539f\u9634\u6027\u4e59\u809d\u7684\u60a3\u8005\uff0c\u6bd4\u8d77e\u6297\u539f\u9633\u6027\u60a3\u8005\uff0c\u4f34\u6709\u7684\u809d\u810f\u75be\u75c5\u66f4\u52a0\u4e25\u91cd\u3002",
"type": 0,
"title": ""
}
},
{
"pk": 6,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u6838\u82f7\u7c7b\uff08\u9178\uff09\u7c7b\u4f3c\u7269\u5728\u5927\u591a\u6570\u9634\u6027\u4e59\u809d\u60a3\u8005\u4e2d\uff0c\u80fd\u591f\u4fdd\u6301\u5bf9\u4e8e\u75c5\u6bd2\u590d\u5236\u7684\u6291\u5236\uff0c\u800c\u4e14\u4eba\u4f53\u5bf9\u5176\u6709\u5f88\u597d\u7684\u836f\u7269\u8010\u53d7\u6027\u3002\u4f46\u662f\uff0c\u975e\u5e38\u96be\u786e\u5b9a\u8fd9\u79cd\u53e3\u670d\u7684\u6297\u75c5\u6bd2\u6cbb\u7597\u662f\u5426\u53ef\u4ee5\u505c\u836f\u3002\u4e0d\u8fc7\uff0c\u4e00\u5e74\u7684\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6cbb\u7597\u53ef\u4ee5\u4f7f\u5f97\u4e00\u4e9b\u9634\u6027\u4e59\u809d\u7684\u60a3\u8005\u80fd\u591f\u83b7\u5f97\u505c\u836f\u540e\u6301\u7eed\u7684\u5e94\u7b54\u6548\u5e94\u3002",
"type": 0,
"title": ""
}
},
{
"pk": 7,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u4e59\u809d\u75c5\u6bd2\uff08HBV DNA\uff09\u5b9a\u91cf\u68c0\u6d4b\u88ab\u5e7f\u6cdb\u5730\u7528\u6765\u8861\u91cf\u4eba\u4f53\u5bf9\u4e8e\u6838\u82f7\uff08\u9178\uff09\u7c7b\u4f3c\u7269\u7684\u5e94\u7b54\uff0c\u4f46\u662f\u901a\u8fc7HBV DNA\u6c34\u5e73\u6765\u76f4\u63a5\u9884\u6d4b\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6cbb\u7597\u6548\u679c\u662f\u56f0\u96be\u7684\u3002",
"type": 0,
"title": ""
}
},
{
"pk": 8,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u8840\u6e05\u4e2d<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\uff08HBsAg\uff09\u4f3c\u4e4e\u53ef\u4ee5\u53cd\u6620\u809d\u810f\u4e2d\u5171\u4ef7\u95ed\u5408\u73af\u72b6DNA\uff08cccDNA\uff09\u7684\u91cf\uff0ccccDNA\u662fHBV\u75c5\u6bd2\u57fa\u56e0\u8f6c\u5f55\u7684\u6a21\u677f\u3002\u6700\u8fd1\u51e0\u9879\u7814\u7a76\u90fd\u5efa\u8bae\u8840\u6e05\u4e2d\u7684HBsAg\u6c34\u5e73\u53ef\u80fd\u6807\u5fd7\u7740\u4eba\u4f53\u5bf9\u4e8e\u5e72\u6270\u7d20\u6cbb\u7597\u5e94\u7b54\u51e0\u7387\u7684\u9ad8\u4e0e\u4f4e\u3002HBsAg\u7684\u4e0b\u964d\u53cd\u6620\u4e86\u809d\u810f\u5185cccDNA\u7684\u4e0b\u964d\u3002",
"type": 0,
"title": ""
}
},
{
"pk": 9,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u4ec0\u4e48\u65f6\u5019\u505a\u7ee7\u7eed\u6cbb\u7597\u8fd8\u662f\u505c\u836f\u6362\u65b9\u6848\u6bd4\u8f83\u5408\u9002\uff1f\r\n\u7528\u4e8e\u9884\u6d4bSR\u7684\u6700\u4f73\u65b9\u6cd5\u662f\u5c06HBsAg\u5b9a\u91cf\u6c34\u5e73\u4e0eHBV DNA\u4e0b\u964d\u6c34\u5e73\u7ed3\u5408\u8d77\u6765\u770b\u3002\u7ecf\u7edf\u8ba1\u5904\u7406\u53d1\u73b0\uff0c\u51b3\u5b9a\u662f\u5426\u7ee7\u7eed\u6cbb\u7597\u4e5f\u4e0d\u9700\u8981\u592a\u665a\uff0c\u6bd4\u598224\u5468\uff0c\u56e0\u4e3a\u4e0e12\u5468\u76f8\u6bd4\uff0c24\u5468\u9884\u6d4bSR\u7684\u4f5c\u7528\u5e76\u6ca1\u6709\u66f4\u597d\u4e00\u4e9b\u3002",
"type": 1,
"title": ""
}
},
{
"pk": 10,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u9884\u6d4b\u6301\u7eed\u5e94\u7b54\uff08SR\uff09\u51e0\u7387\u770b<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\uff08HBsAg\uff09\u4e00\u4e2a\u6307\u6807\u591f\u5417\uff1f\r\n\u7ecf\u6570\u5b66\u7edf\u8ba1\u5904\u7406\u8bc1\u660e\uff0c\u63a5\u53d7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6cbb\u7597\u7684HBeAg\u9634\u6027\u6162\u6027\u4e59\u809d\u60a3\u8005\u5728\u65e9\u671f\u9636\u6bb5\u4ec5\u4ec5\u4f9d\u9760HBsAg\u6c34\u5e73\u6765\u7cbe\u786e\u9884\u6d4b\u6301\u7eed\u5e94\u7b54\uff08SR\uff09\u662f\u4e0d\u53ef\u80fd\u7684\u3002\r\n\u7136\u800c\uff0c\u628a\u7597\u7a0b\u8fc7\u7a0b\u7684\u4e2dHBsAg\u4e0b\u964d\u548c\u75c5\u6bd2\u4e0b\u964d\u60c5\u51b5\u4e24\u8005\u7ed3\u5408\u5728\u4e00\u8d77\uff0c\u4fbf\u80fd\u591f\u5f62\u6210\u4e00\u6761\u660e\u786e\u7684\u505c\u836f\u539f\u5219\u3002",
"type": 1,
"title": ""
}
},
{
"pk": 11,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u6b64\u7814\u7a76\u4e2d\uff0c\u7a76\u7adf\u54ea\u4e00\u90e8\u5206e\u6297\u539f\u9634\u6027\u6162\u4e59\u809d\u60a3\u8005\u63a5\u53d7PEG\u5e72\u6270\u7d20\u6cbb\u7597\u6548\u679c\u76f8\u5bf9\u66f4\u597d\uff1f\r\n\u572812\u5468\u65f6\uff0c\u540c\u65f6\u53d1\u73b0<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\uff08HBsAg\uff09\u4e0b\u964d\u548c\u4e59\u809d\u75c5\u6bd2\uff08HBV DNA\uff09\u4e0b\u964d\u5927\u4e8e2log \u62f7\u8d1d/ml\u7684\u60a3\u8005\u62e5\u6709\u6700\u9ad8\u7684\u83b7\u5f97SR\u7684\u51e0\u7387\uff0839%\uff09\u3002\r\n\u8fd9\u4e00\u7ec4\u4eba\u5e94\u8be5\u88ab\u9f13\u52b1\u5b8c\u6210\u4e3a\u671f48\u5468\u7684\u6cbb\u7597\u3002",
"type": 1,
"title": ""
}
},
{
"pk": 12,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "DNA\u8981\u4e0b\u964d\u5230\u591a\u5c11\u5bf9\u4e8ee\u6297\u539f\uff08HBeAg\uff09\u9634\u6027\u6162\u4e59\u809d\u60a3\u8005\u6700\u5408\u9002?\r\n\u8be5\u7814\u7a76\u628a\u6301\u7eed\u5e94\u7b54\uff08SR\uff09\u5b9a\u4e49\u4e3a\u6cbb\u7597\u7ed3\u675f6 \u4e2a\u6708\u65f6\uff0cHBV DNA \u6c34\u5e73<10,000 \u62f7\u8d1d/mL\uff0c\u5e76\u4e14ALT \u6c34\u5e73\u6062\u590d\u6b63\u5e38\u3002",
"type": 1,
"title": ""
}
},
{
"pk": 13,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u6709\u4e9b\u4eba\u53ef\u80fd\u4f1a\u4e89\u8bae\u8bf4HBV DNA \u7684\u4e0b\u9650\u5e94\u8be5\u66f4\u4f4e\u4e00\u70b9\u3002\u7528\u654f\u611f\u7684PCR \u68c0\u6d4b\u65b9\u6cd5\u68c0\u6d4b\u5230\u6cbb\u7597\u540eHBV DNA \u9634\u6027\u7684\u786e\u662f\u4e00\u4e2a\u4e3b\u8981\u7684\u6cbb\u7597\u7ec8\u70b9\u3002\r\n\u5c3d\u7ba1\u5982\u6b64\uff0c\u5e72\u6270\u7d20\u6cbb\u7597\u7684HBeAg \u9634\u6027\u7684CHB \u75c5\u4eba\u5e38\u5e38\u4e0d\u80fd\u8fbe\u5230\u8fd9\u4e9b\u6cbb\u7597\u7ec8\u70b9\u3002",
"type": 1,
"title": ""
}
},
{
"pk": 14,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u53e6\u5916\uff0c\u5927\u6837\u672c\u7814\u7a76\u8868\u660e\uff0c\u5982\u679cHBeAg \u9634\u6027\u7684CHB \u75c5\u4ebaHBV DNA<10,000 \u62f7\u8d1d /mL\uff0c\u90a3\u4e48\u4ed6\u4eec\u53d1\u5c55\u4e3a\u809d\u786c\u5316\u548c\u809d\u7ec6\u80de\u764c\u7684\u5371\u9669\u6027\u964d\u4f4e\u3002",
"type": 1,
"title": ""
}
},
{
"pk": 15,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u800c\u4e14\uff0c\u672c\u7814\u7a76\u4e2dHBV DNA \u7684\u4e34\u754c\u503c\u4ee5\u53ca\u968f\u8bbf\u671f\u9650\u4e0e\u6700\u8fd1\u7684\u6b27\u6d32\u6307\u5357\u5bf9\u5e72\u6270\u7d20\u6cbb\u7597\u5e94\u7b54\u7684\u5b9a\u4e49\u548c\u51e0\u9879\u91cd\u8981\u7684\u5173\u4e8e\u5e72\u6270\u7d20\u6cbb\u7597\u6162\u6027\u4e59\u809d\u7684\u7814\u7a76\u7684\u968f\u8bbf\u671f\u9650\u5206\u522b\u662f\u4e00\u81f4\u7684\u3002",
"type": 1,
"title": ""
}
},
{
"pk": 16,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u4e3a\u4ec0\u4e48\u672c\u7814\u7a76\u7684\u603b\u4f53\u6301\u7eed\u5e94\u7b54\u51e0\u7387\u6bd4\u8d77\u5176\u4ed6\u7814\u7a76\u4f1a\u8f83\u4f4e\uff0c\u53ea\u670922%\uff1f\r\n\u8be5\u7814\u7a76\u53d7\u8bd5\u8005\u5927\u591a\u6570\u4eba\u90fd\u662f\u767d\u79cd\u4eba\uff0c\u611f\u67d3\u7684HBV\u57fa\u56e0\u578b\u4e3aA\u548cD\uff0cD\u578b\u60a3\u8005\u5e94\u7b54\u6548\u679c\u4f3c\u4e4e\u4f4e\u4e8e\u5176\u4ed6\u57fa\u56e0\u578b\uff0c\u8fd9\u4e5f\u8bb8\u80fd\u89e3\u91ca\u4e3a\u4ec0\u4e48\u6b64\u7814\u7a76\u7684\u603b\u4f53\u7597\u6548\u6b20\u4f73\u3002",
"type": 1,
"title": ""
}
},
{
"pk": 17,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u4e3a\u4ec0\u4e48<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\u6e05\u9664\u662f\u91cd\u8981\u7684\u6cbb\u7597\u7ec8\u70b9\uff1f\r\n\u6cbb\u7597\u4e59\u809d\u7684\u65f6\u5019\uff0c<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\uff08HBsAg\uff09\u7684\u6e05\u9664\u80fd\u591f\u4f7f\u5f97\u7ec4\u7ec7\u5b66\u6539\u5584\uff0c\u964d\u4f4e\u809d\u786c\u5316\u548c\u809d\u7ec6\u80de\u764c\u7684\u53d1\u751f\u7387\uff0c\u4ece\u800c\u63d0\u9ad8\u751f\u5b58\u7387\u3002\u6240\u4ee5\u5b83\u73b0\u5728\u53d8\u6210\u4e86\u91cd\u8981\u7684\u6cbb\u7597\u7ec8\u70b9\u3002",
"type": 0,
"title": ""
}
},
{
"pk": 18,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\u6e05\u9664\u662f\u4e0d\u662f\u5408\u9002\u7684\u77ed\u671f\u6cbb\u7597\u7ec8\u70b9\uff1f\r\n\u4f46\u662f\uff0c<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\uff08\u6e05\u9664\u5e76\u4e0d\u662f\u4e00\u4e2a\u6700\u5408\u9002\u7684\u77ed\u671f\u6cbb\u7597\u7684\u7ec8\u70b9\u56e0\u4e3a\u5728\u63a5\u53d7\u6cbb\u7597\u540e\u5f88\u77ed\u4e00\u6bb5\u65f6\u95f4\u4e4b\u5185\uff0c\u8fd9\u4e2a\u6307\u6807\u88ab\u6e05\u9664\u7684\u51e0\u7387\u5b9e\u5728\u592a\u4f4e\u3002",
"type": 0,
"title": ""
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},
{
"pk": 19,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u4ee4\u4eba\u6ee1\u610f\u7684\u6cbb\u7597\u7ec8\u70b9-e\u6297\u539f\u8840\u6e05\u5b66\u8f6c\u6362\r\n\u6700\u8fd1\u7684\u4e34\u5e8a\u6cbb\u7597\u6307\u5357\u5efa\u8baee\u6297\u539f\uff08HBeAg\uff09\u6301\u4e45\u7684\u8840\u6e05\u5b66\u8f6c\u6362\u662f\u4e00\u4e2a\u4ee4\u4eba\u6ee1\u610f\u7684\u6cbb\u7597\u7ec8\u70b9\uff0c\u5728\u6cbb\u7597e\u6297\u539f\u9633\u6027\u6162\u6027\u4e59\u809d\u60a3\u8005\u65f6\u5019\u3002\u56e0\u4e3a\u8fd9\u79cd\u8f6c\u6362\u548c\u826f\u597d\u7684\u9884\u540e\u6709\u5173\u3002\r\n\u901a\u8fc7\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6cbb\u7597e\u6297\u539f\u9633\u6027\u6162\u6027\u4e59\u809d\u5df2\u7ecf\u88ab\u88ab\u8ba4\u53ef\u4e3a\u662f\u4e00\u7ebf\u6cbb\u7597\u9009\u62e9\u65b9\u6848\uff0c\u56e0\u4e3a\u5b83\u80fd\u591f\u5728\u6709\u9650\u7684\u65f6\u95f4\u5e26\u6765\u6cbb\u7597\u540e\u7684\u6301\u4e45\u5e94\u7b54\u3002\r\n\u5927\u7ea6\u4e09\u5206\u4e4b\u4e00\u7684e\u6297\u539f\u9633\u6027\u6162\u4e59\u809d\u5728\u63a5\u53d7\u5b8c\u6574\u7684\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6cbb\u7597\u7684\u60a3\u8005\uff0c\u5728\u6cbb\u7597\u7ed3\u675f\u540e6\u4e2a\u6708\u53d1\u751f\u4e86e\u6297\u539f\u8840\u6e05\u5b66\u8f6c\u6362\u3002",
"type": 0,
"title": ""
}
},
{
"pk": 20,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u5224\u522b\u6cbb\u7597\u65e9\u671f\u5e94\u7b54\u7684\u610f\u4e49\r\n\uff08\u65e0\u8bba\u662f\u6cbb\u7597\u524d\u8fd8\u662f\u6cbb\u7597\u671f\u95f4\uff09\u6cbb\u7597\u65e9\u671f\u65f6\u5019\u5bf9\u4e8e\u60a3\u8005\u5e94\u7b54\u7684\u5224\u522b\u5bf9\u4e8e\u4e34\u5e8a\u533b\u5e08\u662f\u5f88\u6709\u5e2e\u52a9\u7684\uff0c\u56e0\u4e3a\u8fd9\u80fd\u591f\u8ba9\u4e34\u5e8a\u533b\u5e08\u5728\u90a3\u4e9b\u6700\u6709\u53ef\u80fd\u53d1\u751f\u5e94\u7b54\u7684\u4eba\u8eab\u4e0a\u4f7f\u7528\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u6cbb\u7597\uff0c\u800c\u90a3\u4e9b\u5bf9\u4e8e\u5e72\u6270\u7d2048\u5468\u6807\u51c6\u7597\u7a0b\u7684\u6cbb\u7597\u5c06\u6765\u4e0d\u5927\u53ef\u80fd\u53d1\u751f\u5e94\u7b54\u7684\u60a3\u8005\u5e94\u8be5\u5373\u4f7f\u8c03\u6574\u6cbb\u7597\u65b9\u6848\u3002\r\n\u80fd\u591f\u5728\u65e9\u4e9b\u65f6\u5019\u80fd\u591f\u8fa8\u8ba4\u51fa\u60a3\u8005\u4e0d\u9002\u5408\u5e72\u6270\u7d20\u6cbb\u7597\uff0c\u6216\u8005\u8bf4\u5bf9\u4e8e\u5e72\u6270\u7d20\u6cbb\u7597\u4e0d\u56de\u5e94\u7b54\uff0c\u4e5f\u80fd\u591f\u9632\u6b62\u60a3\u8005\u7ecf\u53d7\u4e0d\u5fc5\u8981\u7684\u526f\u4f5c\u7528\u3002",
"type": 0,
"title": ""
}
},
{
"pk": 21,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u5173\u4e8ecccDNA\u548c<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\u7684\u5173\u7cfb\uff0c\u4ece\u673a\u7406\u4e0a\u89e3\u91ca\u5b9a\u91cf\u68c0\u6d4b<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\u7684\u91cd\u8981\u6027\uff1a\r\n\r\n<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\uff08HBsAg\uff09\u548c\u5171\u4ef7\u95ed\u5408\u73af\u72b6\uff08cccDNA\uff09\u6709\u6b63\u76f8\u5173\uff0c\u4e5f\u5c31\u662f\u8bf4<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\u6c34\u5e73\u5347\u9ad8\u65f6cccDNA\u4e5f\u4f1a\u5347\u9ad8\uff0c\u53cd\u4e4b\u4ea6\u7136\u3002\r\n\r\ncccDNA\u662f\u4e59\u809d\u75c5\u6bd2\u524d\u57fa\u56e0\u7ec4RNA\u590d\u5236\u7684\u539f\u59cb\u6a21\u677f\uff0c\u867d\u7136\u5176\u542b\u91cf\u8f83\u5c11\uff0c\u6bcf\u4e2a\u809d\u7ec6\u80de\u5185\u53ea\u6709\u7ea65\uff5e50\u4e2a\u62f7\u8d1d\uff0c\u6545cccDNA\u53cd\u6620\u4e86\u611f\u67d3\u75c5\u6bd2\u7684\u809d\u7ec6\u80de\u7684\u6570\u91cf\uff0c\u800c\u4e14\u4ed6\u626e\u6f14\u7740\u75c5\u6bd2\u57fa\u56e0\u8f6c\u5f55\u6a21\u677f\u7684\u89d2\u8272\u3002\r\n\r\n\u5373\u4f7f\u4e59\u809d\u75c5\u6bd2\uff08HBV\uff09DNA\u68c0\u6d4b\u4e0d\u5230\uff08\u5373\u5316\u9a8c\u5355\u4e0a\u663e\u793a\u9634\u6027\uff09\uff0c\u4f46cccDNA\u5982\u679c\u7ee7\u7eed\u5b58\u5728\u4e8e\u809d\u7ec6\u80de\u4e2d\uff0c\u90a3\u4e48\u60a3\u8005\u8fd8\u662f\u9762\u4e34\u7740HBV\u611f\u67d3\u590d\u53d1\u7684\u53ef\u80fd\u6027\u7684\u3002\u5e72\u6270\u7d20\u7684\u514d\u75ab\u8c03\u8282\u6d3b\u6027\u80fd\u591f\u4fc3\u4f7f\u75c5\u6bd2T\u7ec6\u80de\u7684\u6d3b\u5316\uff0c\u4ece\u800c\u6e05\u9664\u611f\u67d3\u7684\u809d\u7ec6\u80de\uff0c\u4e5f\u5c31\u51cf\u5c11\u4e86cccDNA\u7684\u6570\u91cf\u3002\r\n\r\n\u603b\u7ed3\u4e0a\u9762\u51e0\u70b9\uff0c\u5b9a\u91cf\u68c0\u6d4b<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\u662f\u4e00\u4e2a\u975e\u5e38\u5408\u9002\u7684\u65b9\u6cd5\u6765\u68c0\u6d4b\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u5bf9\u4e8e\u88ab\u611f\u67d3\u7684\u809d\u7ec6\u80de\u7684\u514d\u75ab\u6e05\u9664\u60c5\u51b5\u548c\u5bf9cccDNA\u7684\u6d88\u9664\u60c5\u51b5\u3002",
"type": 1,
"title": ""
}
},
{
"pk": 22,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u5bf9\u805a\u4e59\u4e8c\u9187\u5e72\u6270\u7d20\u4ea7\u751f\u514d\u75ab\u5e94\u7b54\u7684\u60a3\u8005\u548c\u6ca1\u6709\u4ea7\u751f\u514d\u75ab\u5e94\u7b54\u7684\u60a3\u8005\uff0c\u5728\u6cbb\u7597\u671f\u95f4<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\u7684\u4e0b\u964d\u7a0b\u5ea6\u662f\u4e0d\u540c\u7684\u3002\u5728\u6cbb\u7597\u671f\u95f4\uff0c\u4f4e<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\u6c34\u5e73\u548c\u66f4\u9ad8\u7684\u5e94\u7b54\u7387\u6709\u5173\u3002",
"type": 1,
"title": ""
}
},
{
"pk": 23,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u6cbb\u7597\u9636\u6bb5\u7684\u65e9\u671f\u5e94\u7b54\uff0c\u8bf8\u5982<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\u4e0b\u964d\u663e\u8457\uff0c\u5bf9\u4e8e\u60a3\u8005\u575a\u6301\u5b8c\u621048\u5468\u7597\u7a0b\u7684\u6cbb\u7597\u662f\u4e00\u4e2a\u9f13\u52b1\u3002",
"type": 1,
"title": ""
}
},
{
"pk": 24,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u7528\u4e8e\u9884\u6d4b\u6301\u7eed\u5e94\u7b54\uff08SR\uff09\u7684\u6700\u4f73\u65b9\u6cd5\u662f\u5c06<a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a>\uff08HBsAg\uff09\u5b9a\u91cf\u6c34\u5e73\u4e0e\u4e59\u809d\u75c5\u6bd2\uff08HBV\uff09 DNA\u4e0b\u964d\u6c34\u5e73\u7ed3\u5408\u8d77\u6765\u770b\u3002\u7ecf\u7edf\u8ba1\u5904\u7406\u53d1\u73b0\uff0c\u51b3\u5b9a\u662f\u5426\u7ee7\u7eed\u6cbb\u7597\u4e5f\u4e0d\u9700\u8981\u592a\u665a\uff0c\u6bd4\u598224\u5468\uff0c\u56e0\u4e3a\u4e0e12\u5468\u76f8\u6bd4\uff0c24\u5468\u9884\u6d4bSR\u7684\u4f5c\u7528\u5e76\u6ca1\u6709\u66f4\u597d\u4e00\u4e9b\u3002",
"type": 1,
"title": ""
}
},
{
"pk": 25,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u4e59\u578b\u809d\u708e\u662f\u4e00\u4e2a\u5168\u7403\u8303\u56f4\u5185\u4e3b\u8981\u7684\u5065\u5eb7\u95ee\u9898\u3002\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\uff08WHO\uff09\u66fe\u62a5\u9053\u5927\u7ea6\u5168\u7403\u6709\u8d85\u8fc74\u4ebf\u4e59\u809d\u75c5\u6bd2\u643a\u5e26\u8005\uff0c\u5c06\u8fd175%\u7684\u643a\u5e26\u8005\u5c45\u4f4f\u5728\u4e9a\u6d32\u548c\u897f\u592a\u5e73\u6d0b\u5730\u533a\u3002\u5728\u8fd9\u4e9b\u5730\u533a\uff0cHBV\u611f\u67d3\u7ecf\u5e38\u53d1\u751f\u5728\u56f4\u4ea7\u671f\u548c\u5e7c\u513f\u65f6\u671f\u3002\r\n\u5927\u591a\u6570\u6765\u81ea\u8fd9\u4e9b\u5730\u533a\u7684\u60a3\u8005\u662f\u5178\u578b\u7684e\u6297\u539f\uff08HBeAg\uff09\u9633\u6027\u6162\u6027\u4e59\u578b\u809d\u708e\u60a3\u8005\uff0c\u4ed6\u4eec\u4f53\u5185\u6709\u7740\u9ad8\u6c34\u5e73\u7684\u4e59\u809d\u75c5\u6bd2\uff0c\u5728\u611f\u67d3\u540e\u768410-30\u5e74\uff0c\u4ed6\u4eec\u4f1a\u9010\u6e10\u53d1\u5c55\u6210\u4e25\u91cd\u7684\u809d\u708e\uff0c<a href=\"#jargon-1\" class=\"jargon\">\u8c37\u4e19\u8f6c\u6c28\u9176</a>\uff08ALT\uff09\u4f1a\u4e0a\u5347\u3002\u76f8\u53cd\uff0c\u5728\u7ae5\u5e74\u665a\u671f\u3001\u9752\u6625\u671f\u3001\u6210\u5e74\u540e\u611f\u67d3\u7684\u60a3\u8005\u4f1a\u5728\u611f\u67d3\u540e\u5f88\u77ed\u4e00\u6bb5\u65f6\u95f4\u5185\u51fa\u73b0\u8c37\u4e19\u8f6c\u6c28\u9176\u5347\u9ad8\u3002\r\n\u5c3d\u7ba1\u81ea\u53d1\u7684e\u6297\u539f\u8840\u6e05\u5b66\u8f6c\u6362\u4f1a\u5728\u5927\u591a\u6570e\u6297\u539f\u9633\u6027\u7684\u60a3\u8005\u4e2d\u51fa\u73b0\uff0c\u4f46\u662f\u809d\u708e\u7684\u6301\u7eed\u65f6\u95f4\u4f1a\u53d8\u957f\u800c\u4e14\u75c5\u75c7\u4f1a\u53d8\u5f97\u8d8a\u6765\u8d8a\u4e25\u91cd\uff0c\u53ef\u80fd\u53d1\u5c55\u6210\u809d\u786c\u5316\u3002\u56e0\u6b64\uff0c\u5728ALT\u51fa\u73b0\u5347\u9ad8\u540e\u76843\u52306\u4e2a\u6708\u5185\u5982\u679c\u4e59\u809d\u75c5\u6bd2\uff08HBV\uff09DNA\u59cb\u7ec8\u4fdd\u6301\u9ad8\u6c34\u5e73\u7684e\u6297\u539f\u9633\u6027\u60a3\u8005\u5e94\u8be5\u63a5\u53d7\u6297\u75c5\u6bd2\u6cbb\u7597\u3002",
"type": 0,
"title": "\u4e59\u809d\u6982\u51b5"
}
},
{
"pk": 26,
"model": "sciblog.knowledgepiece",
"fields": {
"content": "\u4e0d\u7ba1\u662f\u7528\u4ec0\u4e48\u6297\u75c5\u6bd2\u836f\u7269\uff0c\u6210\u529f\u6cbb\u7597\u6162\u6027\u4e59\u809d\u75c5\u6bd2\u611f\u67d3\u90fd\u662f\u6307e\u6297\u539f\u7684\u6e05\u9664\u3001\u8840\u6e05\u4e59\u809d\u75c5\u6bd2DNA\u6c34\u5e73\u7684\u4e0b\u964d\u4ee5\u53ca<a href=\"#jargon-1\" class=\"jargon\">\u8c37\u4e19\u8f6c\u6c28\u9176</a>\u6c34\u5e73\u6062\u590d\u6b63\u5e38\uff0c\u56e0\u4e3a\u8fd9\u4e9b\u6307\u6807\u53d8\u5316\u90fd\u548c\u826f\u597d\u7684\u957f\u671f\u7597\u6548\u6709\u5173\u8054\u3002\r\n<p>\r\n\u5728e\u6297\u539f\u9633\u6027\u7684\u60a3\u8005\u4e2d\uff0c\u8840\u6e05\u4e2d\u6301\u4e45\u7684e\u6297\u539f\u6e05\u9664\u548c\u65e5\u540e\u8840\u6e05\u4e2d<a href=\"#jargon-2\" class=\"jargon\"><a href=\"#jargon-2\" class=\"jargon\">\u8868\u9762\u6297\u539f</a></a>\uff08HBsAg\uff09\u7684\u6e05\u9664\u3001\u6f14\u53d8\u6210\u809d\u786c\u5316\u548c\u809d\u7ec6\u80de\u764c\u7684\u51e0\u7387\u7684\u964d\u4f4e\u4ee5\u53ca\u6700\u7ec8\u751f\u5b58\u8d28\u91cf\u7684\u6539\u5584\u6709\u5173\u3002</p>",
"type": 0,
"title": "\u6cbb\u7597\u4e59\u809d\u7684\u666e\u904d\u7684\u6cbb\u7597\u7ec8\u70b9"
}
},
{
"pk": 27,
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"fields": {
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"type": 0,
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}
},
{
"pk": 28,
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{
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"figures": [],
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1
],
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},
{
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2,
3
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2,
3
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2
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},
{
"pk": 3,
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1
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},
{
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{
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{
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{
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|